Endothelial injury and decline in lung function in persons living with HIV: a prospective Danish cohort study including 698 adults
C Rønn, AD Knudsen, NS Arentoft, RF Thudium… - Frontiers in …, 2024 - frontiersin.org
Objectives Endothelial injury may promote declining lung function. We aimed to investigate
in well-treated persons living with HIV (PLWH) whether elevated levels of thrombomodulin …
in well-treated persons living with HIV (PLWH) whether elevated levels of thrombomodulin …
Intraoperative systemic biomarkers predict post-liver transplantation acute kidney injury
LC Cezar, GC Meneses… - European Journal of …, 2021 - journals.lww.com
Objective Liver transplant (LT) is a definitive therapeutic option for patients with chronic liver
disease. However, acute kidney injury after LT (post-LT AKI) is a frequent complication that …
disease. However, acute kidney injury after LT (post-LT AKI) is a frequent complication that …
Neuraxial anesthesia is less harmful to the endothelial glycocalyx during elective joint surgery compared to general anesthesia
D Astapenko, J Pouska, J Benes… - Clinical …, 2019 - content.iospress.com
BACKGROUND: Damage of the endothelial glycocalyx (EG) has been described during
surgery, but the effect of different anesthesia techniques remains unknown. Perfused …
surgery, but the effect of different anesthesia techniques remains unknown. Perfused …
Evaluation of endothelial glycocalyx in healthy volunteers–An observational study
D Astapenko, A Ticha, A Tomasova… - Clinical …, 2020 - content.iospress.com
BACKGROUND: Endothelial glycocalyx (EG) is a carbohydrate-rich gel-like mesh covering
the apical surface of endothelial cells. It has been linked to the microvascular …
the apical surface of endothelial cells. It has been linked to the microvascular …
Direct evidence of endothelial dysfunction and glycocalyx loss in dermal biopsies of patients with chronic kidney disease and their association with markers of volume …
J Koch, RS Hijmans, M Ossa Builes… - Frontiers in Cell and …, 2021 - frontiersin.org
Cardiovascular morbidity is a major problem in patients with chronic kidney disease (CKD)
and endothelial dysfunction (ED) is involved in its development. The luminal side of the …
and endothelial dysfunction (ED) is involved in its development. The luminal side of the …
[HTML][HTML] Reduced glomerular endothelial thrombomodulin is associated with glomerular macrophage infiltration in diabetic nephropathy
CCL van Aanhold, KL Dijkstra, M Bos… - The American Journal of …, 2021 - Elsevier
The endothelial glycoprotein thrombomodulin regulates coagulation, inflammation, and
apoptosis. In diabetic mice, reduced thrombomodulin function results in diabetic …
apoptosis. In diabetic mice, reduced thrombomodulin function results in diabetic …
Sodium and water dynamics in the progression of chronic kidney disease: mechanisms and clinical significance
Aim Lifestyle modifications can postpone the progression of chronic kidney disease toward
its terminal stage. This mini-review aims to explore the impact of salt and water intake on the …
its terminal stage. This mini-review aims to explore the impact of salt and water intake on the …
[HTML][HTML] Protocol for intraoperative assessment of the human cerebrovascular glycocalyx
Introduction Adequate functioning of the blood–brain barrier (BBB) is important for brain
homoeostasis and normal neuronal function. Disruption of the BBB has been described in …
homoeostasis and normal neuronal function. Disruption of the BBB has been described in …
Mutations in the heparan sulfate backbone elongating enzymes EXT1 and EXT2 have no major effect on endothelial glycocalyx and the glomerular filtration barrier
R Khalil, MGS Boels… - Molecular Genetics and …, 2022 - Springer
In this study, the effect of heterozygous germline mutations in the heparan sulfate (HS)
glycosaminoglycan chain co-polymerases EXT1 and EXT2 on glomerular barrier function …
glycosaminoglycan chain co-polymerases EXT1 and EXT2 on glomerular barrier function …
The effect of fluid loading and hypertonic saline solution on cortical cerebral microcirculation and glycocalyx integrity
V Dostalova, D Astapenko, V Dostalova Jr… - Journal of …, 2019 - journals.lww.com
Background: Fluid loading and hyperosmolar solutions can modify the cortical brain
microcirculation and the endothelial glycocalyx (EG). This study compared the short-term …
microcirculation and the endothelial glycocalyx (EG). This study compared the short-term …