Investigational use of mesenchymal stem/stromal cells and their secretome as add-on therapy in severe respiratory virus infections: challenges and perspectives

S Mattoli, M Schmidt - Advances in Therapy, 2023 - Springer
Serious manifestations of respiratory virus infections such as influenza and coronavirus
disease 2019 (COVID-19) are associated with a dysregulated immune response and …

Cancer and COVID-19: unravelling the immunological interplay with a review of promising therapies against severe SARS-CoV-2 for cancer patients

Y Leyfman, N Emmanuel, GP Menon, M Joshi… - Journal of Hematology & …, 2023 - Springer
Cancer patients, due to their immunocompromised status, are at an increased risk for severe
SARS-CoV-2 infection. Since severe SARS-CoV-2 infection causes multiple organ damage …

[HTML][HTML] Stem cell-based therapy for COVID-19

X Chen, B Liu, C Li, Y Wang, S Geng, X Du… - International …, 2023 - Elsevier
Abstract While The World Health Organization (WHO) has announced that COVID-19 is no
longer a public health emergency of international concern (PHEIC), the risk of reinfection …

Mesenchymal stem cell therapy for COVID-19 infection

SMM Alavi-Dana, Y Gholami, M Meghdadi… - …, 2023 - Springer
COVID-19 emerged in December 2019 in Wuhan, China, spread worldwide rapidly, and
caused millions of deaths in a short time. Many preclinical and clinical studies were …

Scale-up of academic mesenchymal stromal cell production

C Laroye, M Gauthier, J Morello, N Charif… - Journal of Clinical …, 2023 - mdpi.com
Background: Many clinical trials have reported the use of mesenchymal stromal cells
(MSCs) following the indication of severe SARS-CoV-2 infection. However, in the COVID19 …

Mesenchymal Stem Cell Priming: Potential Benefits of Administration of Molecular Hydrogen

MY Artamonov, TW LeBaron, FA Pyatakovich… - Pharmaceuticals, 2024 - mdpi.com
Stem cell therapy has emerged as a promising avenue for regenerative medicine, offering
the potential to treat a wide range of debilitating diseases and injuries. Among the various …

Treatment of COVID-19-associated ARDS with umbilical cord-derived mesenchymal stromal cells in the STROMA-CoV-2 multicenter randomized double-blind trial …

A Sitbon, C Hauw-Berlemont, M Mebarki… - Stem Cell Research & …, 2024 - Springer
Abstract Background The STROMA-CoV-2 study was a French phase 2b, multicenter,
double-blind, randomized, placebo-controlled clinical trial that did not identify a significant …

The promising approach of MSCs therapy for COVID-19 treatment

R Samanipour, S Tabatabaee, M Delyanee… - Cell and Tissue …, 2023 - Springer
Several ongoing investigations have been founded on the development of an optimized
therapeutic strategy for the COVID-19 virus as an undeniable acute challenge for human life …

Current and Emerging Therapies for COVID-19 in Lung Transplantation

DZP Friedman, NN Pettit, E MacKenzie… - Current Pulmonology …, 2023 - Springer
Abstract Purpose of Review The landscape of the coronavirus disease 2019 (COVID-19)
pandemic has rapidly changed over the past 3 years. Paralleling this evolution, the scientific …

[HTML][HTML] Controversies regarding transplantation of mesenchymal stem cells

T Velikova, T Dekova, DG Miteva - World Journal of Transplantation, 2024 - wjgnet.com
Mesenchymal stem cells (MSCs) have tantalized regenerative medicine with their
therapeutic potential, yet a cloud of controversies looms over their clinical tran splantation …