[HTML][HTML] F-actin nanostructures rearrangements and regulation are essential for SARS-CoV-2 particle production in host pulmonary cells

J Swain, P Merida, K Rubio, D Bracquemond, A Neyret… - Iscience, 2023 - cell.com
Our study focused on deciphering the role of F-actin and related regulatory factors during
SARS-CoV-2 particle production and transmission in human pulmonary cells. Quantitative …

Tunneling nanotubes and tumor microtubes—Emerging data on their roles in intercellular communication and pathophysiology: Summary of an International FASEB …

E Lou, C Vérollet, F Winkler, C Zurzolo… - 2024 - Wiley Online Library
In the past decade, there has been a steady rise in interest in studying novel cellular
extensions and their potential roles in facilitating human diseases, including neurologic …

[PDF][PDF] Hijacking intercellular trafficking for the spread of protein aggregates in neurodegenerative diseases: A focus on tunneling nanotubes (TNTs)

R Chakraborty, S Belian, C Zurzolo - Extracell. Vesicles Circ. Nucleic Acids, 2023 - f.oaes.cc
Over the years, the influence of secretory mechanisms on intercellular communication has
been extensively studied. In the central nervous system (CNS), both trans-synaptic …

Neurons cytoskeletal architecture remodeling during the replication cycle of mouse coronavirus MHV-JHM: a morphological in vitro study

M Bartak, P Bąska, M Chodkowski, B Tymińska… - BMC Veterinary …, 2024 - Springer
Nowadays, the population is still struggling with a post-COVID19 syndrome known as long
COVID, including a broad spectrum of neurological problems. There is an urgent need for a …

SARS-CoV-2 egress from Vero cells: a morphological approach

LA Caldas, FA Carneiro, I Augusto, IA Corrêa… - Histochemistry and Cell …, 2024 - Springer
Despite being extensively studied because of the current coronavirus disease 2019 (COVID-
19) pandemic, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interactions …

Environmental and genetic drivers of population differences in SARS-CoV-2 immune responses

Y Aquino, A Bisiaux, Z Li, M O'neill, J Mendoza-Revilla… - bioRxiv, 2022 - biorxiv.org
Humans display vast clinical variability upon SARS-CoV-2 infection–, partly due to genetic
and immunological factors. However, the magnitude of population differences in immune …

Proteomic landscape of tunneling nanotubes reveals CD9 and CD81 tetraspanins as key regulators

RN Manzano, T Chaze, E Rubinstein, M Matondo… - bioRxiv, 2022 - biorxiv.org
Tunneling nanotubes (TNTs) are open actin-and membrane-based channels, connecting
remote cells and allowing direct transfer of cellular material (eg vesicles, mRNAs, protein …

Impact of variants and vaccination on nasal immunity across three waves of SARS-CoV-2

JM Long, VN Miao, AH Owings, Y Tang, JD Bromley… - bioRxiv, 2024 - biorxiv.org
SARS-CoV-2 infection and COVID-19 disease vary with respect to viral variant and host
vaccination status. However, how vaccines, emergent variants, and their intersection shift …

SARS-CoV-2 infected cells sprout actin-rich filopodia that facilitate viral invasion

Y Zhang, X Zhang, Z Li, W Zhao, H Yang, D Tang… - bioRxiv, 2022 - biorxiv.org
Emerging COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) poses a great threat to human health and economics. Although SARS-CoV-2 …

Intercellular mitochondrial transfer as a rescue mechanism in response to protein import failure

HI Needs, GC Pereira, E Glover, A Witt, W Hübner… - bioRxiv, 2022 - biorxiv.org
Mitochondria are the powerhouses of eukaryotic cells, composed mostly of nuclear-encoded
proteins imported from the cytosol. Thus, problems with the import machinery will disrupt …