Tumors of the mediastinum represent a wide diversity of disease states. The location and
composition of a mass is critical to narrowing the differential diagnosis. The most common …

The problems with anticancer therapy are resistance and toxicity. From 3000 Cisplatin
derivatives tested as antitumor agents, most of them have been rejected, due to toxicity. The …

Introduction Thymic carcinoma (TC) is a rare cancer with a poor prognosis and limited
treatment options, especially after relapse. Methods In this open-label, two-stage …

In this largest phase II trial with advanced thymic carcinoma (TC), carboplatin and paclitaxel
(CbP) showed promising efficacy in advanced TC when compared with anthracycline-based …

Masses in the anterior mediastinum can be neoplasms (eg, thymomas, thymic carcinomas,
or lung metastases) or non-neoplastic conditions (eg, intrathoracic goiter). Thymomas are …

Purpose Thymic malignancies, comprising thymoma and thymic carcinoma, are rare.
Consequently, optimal chemotherapy for advanced thymic malignancies remains …

Cancer is the second leading cause of mortality worldwide accounting for almost 10 million
deaths in 2020. Current standard of care treatment varies depending on the type and stage …

Objectives: Identify the etiology of anterior mediastinal masses. Outline the evaluation of
anterior mediastinal mass. Review the treatment and management options available for an …

BACKGROUND: Thymic carcinoma is a rare tumor. Limited data are available regarding the
effectiveness of treatment and the prognosis of thymic carcinoma. The present study aimed …

BACKGROUND: Thymic carcinoma is a very rarely encountered neoplasm and no optimal
chemotherapeutic regimen has been established yet. METHODS: The records of previously …