G protein-coupled receptors (GPCRs) are the largest family of membrane-bound receptors
and also the targets of many drugs. Understanding of the functional significance of the wide …

G protein–coupled receptors (GPCRs) are the largest family of cell surface receptors. Class
B1 GPCRs constitute a subfamily of 15 receptors that characteristically contain large …

G protein-coupled, seven-transmembrane segment receptors (GPCRs or 7TM receptors),
with more than 1000 different members, comprise the largest superfamily of proteins in the …

Peptide hormones within the secretin-glucagon family are expressed in endocrine cells of
the pancreas and gastrointestinal epithelium and in specialized neurons in the brain, and …

The superfamily of G protein-coupled receptors (GPCRs) contains immense structural and
functional diversity and mediates a myriad of biological processes upon activation by …

A relation between the chemical structure of a xenobiotic and its steroidal action has not yet
been clearly established. Thus, it is not possible to define the estrogenic potency of different …

Primary canalicular bile undergoes a process of fluidization and alkalinization along the
biliary tract that is influenced by several factors including hormones, innervation …

Class BG protein-coupled receptors are composed of an extracellular domain (ECD) and a
seven-transmembrane (7TM) domain, and their signalling is regulated by peptide hormones …

Secretin and vasoactive intestinal peptide receptors: Members of a unique family of G
protein–coupled receptors - ScienceDirect Skip to main contentSkip to article Elsevier logo …

Receptor-mediated endocytosis has been observed after agonist occupation of several G
protein-coupled receptors, which contributes to the desensitization response to agonist …