The reaction takes place at a specialized metal center that dramatically increases the acidity
of H2 and leads to a heterolytic splitting of the molecule which is strongly accelerated by the …

If the atmosphere of the early Earth was hydrogen-rich, 1 it is reasonable to think that
hydrogenases, the enzymes enabling cells to use molecular hydrogen, were probably …

The utilization of hydrogen by micro-organisms as a source of reducing power or of protons
as final electron acceptors is mediated by metalloenzymes called hydrogenases. The need …

Hydrogenases (H2ases) catalyze the reversible oxidation of molecular hydrogen and play a
central role in microbial energy metabolism. Most of these enzymes are found in Archaea …

Cyanobacteria may possess two distinct nickel-iron (NiFe)-hydrogenases: an uptake
enzyme found in N 2-fixing strains, and a bidirectional one present in both non-N 2-fixing …

There continues to be widespread interest in the applications of hydrogen as a clean fuel
and its potential for local electricity production and use in transport. Recent years have seen …

Enzymes possessing the capacity to oxidize molecular hydrogen have developed
convergently three class of enzymes leading to:[FeFe]-,[NiFe]-, and [FeS]-cluster-free …

Hydrogenases (H 2 ases) are metalloproteins. The great majority of them contain iron-sulfur
clusters and two metal atoms at their active center, either a Ni and an Fe atom, the [NiFe]-H 2 …

The Tat (twin a rginine t ranslocation) protein transport system functions to export folded
protein substrates across the bacterial cytoplasmic membrane and to insert certain integral …

[NiFe]-hydrogenases catalyze the reversible conversion of hydrogen gas into protons and
electrons and are vital metabolic components of many species of bacteria and archaea. At …