Liver sinusoidal endothelial cells (LSECs) form the wall of the hepatic sinusoids. Unlike
other capillaries, they lack an organized basement membrane and have cytoplasm that is …

Oligonucleotides (oligos) have been under clinical development for approximately the past
30 years, beginning with antisense oligonucleotides (ASOs) and apatmers and followed …

Liver sinusoidal endothelial cells (LSECs) are highly specialized endothelial cells
representing the interface between blood cells on the one side and hepatocytes and hepatic …

The advances in hematopoietic cell transplantation (HCT) over the last decade have led to a
transplant-related mortality below 15%. Hepatic sinusoidal obstruction syndrome/veno …

Drug-induced liver injury (DILI) is an important clinical problem, which has received more
attention in recent decades. It can be induced by small chemical molecules, biological …

Veno-occlusive disease, also known as sinusoidal obstruction syndrome (VOD/SOS), is a
potentially life-threatening complication of allogeneic or autologous hematopoietic stem cell …

Secondary immunodeficiency is reported in most patients with hematological malignancies
such as chronic lymphocytic leukemia and multiple myeloma. The aim of our review was to …

The incidence of esophageal adenocarcinoma (EAC) has increased in recent decades, and
its 5-year survival rate is less than 20%. As a well-established precursor, patients with …

Introduction: There is a limited array of currently available medicinals that are useful for
either the prevention, mitigation or treatment of bodily injuries arising from ionizing radiation …

Hepatic sinusoidal obstruction syndrome (HSOS) can be caused by the intake of
pyrrolizidine alkaloids (PAs). To date, PAs-induced HSOS has not been extensively studied …