Peripheral sTREM2-related inflammatory activity alterations in early-stage Alzheimer's disease
GE Weber, M Khrestian, ED Tuason… - The Journal of …, 2022 - journals.aai.org
Alzheimer's disease (AD) has been linked to multiple immune system–related genetic
variants. Triggering receptor expressed on myeloid cells 2 (TREM2) genetic variants are risk …
variants. Triggering receptor expressed on myeloid cells 2 (TREM2) genetic variants are risk …
[HTML][HTML] Inflammation in the CNS: Understanding Various Aspects of the Pathogenesis of Alzheimer's Disease
J Doroszkiewicz, P Mroczko… - Current Alzheimer …, 2022 - ncbi.nlm.nih.gov
Alzheimer's disease is a progressive and deadly neurodegenerative disorder and one of the
most common causes of dementia globally. Current, insufficiently sensitive and specific …
most common causes of dementia globally. Current, insufficiently sensitive and specific …
Prodromic Inflammatory–Oxidative Stress in Peritoneal Leukocytes of Triple-Transgenic Mice for Alzheimer's Disease
N Ceprián, I Martínez de Toda, I Maté… - International Journal of …, 2024 - mdpi.com
Inflammatory–oxidative stress is known to be pivotal in the pathobiology of Alzheimer's
disease (AD), but the involvement of this stress at the peripheral level in the disease's onset …
disease (AD), but the involvement of this stress at the peripheral level in the disease's onset …
Saffron reduces some inflammation and oxidative stress markers in donepezil-treated mild-to-moderate Alzheimer's disease patients: A randomized double-blind …
LR Marzabadi, SMB Fazljou, M Araj-Khodaei… - Journal of Herbal …, 2022 - Elsevier
Background Mounting evidence indicates the possible positive effects of Crocus sativus
(saffron) on cognitive function in patients with Alzheimer's Disease (AD). This study …
(saffron) on cognitive function in patients with Alzheimer's Disease (AD). This study …
[HTML][HTML] Roles of Cytokines in Alzheimer's Disease
Z Chen, YL Balachandran, WP Chong… - International Journal of …, 2024 - mdpi.com
The neuroimmune system is a collection of immune cells, cytokines, and the glymphatic
system that plays a pivotal role in the pathogenesis and progression of Alzheimer's disease …
system that plays a pivotal role in the pathogenesis and progression of Alzheimer's disease …
[HTML][HTML] A systematic review and Bayesian meta-analysis assessing intelectin-1 in cancer patients and healthy individuals
DR Paval, TG Di Virgilio, RJE Skipworth… - Frontiers in …, 2024 - frontiersin.org
Background Intelectin-1 (ITLN1) is an adipokine with multiple physiological functions,
including a role in tumour formation and development. Previous research reported variable …
including a role in tumour formation and development. Previous research reported variable …
Thymoquinone (TQ) demonstrates its neuroprotective effect via an anti-inflammatory action on the Aβ(1–42)-infused rat model of Alzheimer's disease
ABSTRACT OBJECTIVES: Alzheimer's disease (AD) is a severe neurodegenerative disease
with presentation of the neuronal death, memory loss and cognitive decline. The relationship …
with presentation of the neuronal death, memory loss and cognitive decline. The relationship …
Microdose lithium treatment reduced inflammatory factors and neurodegeneration in organotypic hippocampal culture of old SAMP-8 mice
M Toricelli, SR Evangelista, HS Buck… - Cellular and Molecular …, 2021 - Springer
It was already shown that microdoses of lithium carbonate (Li 2 CO 3) promoted memory
stabilization in humans and mice. Prolonged treatment also reduced neuronal loss and …
stabilization in humans and mice. Prolonged treatment also reduced neuronal loss and …
Multiple adipokines predict dementia severity as measured by δ: Replication across biofluids and cohorts
Background: We have explored dementia's blood-based protein biomarkers in the Texas
Alzheimer's Research and Care Consortium (TARCC) study. Among them are adipokines …
Alzheimer's Research and Care Consortium (TARCC) study. Among them are adipokines …
[HTML][HTML] Hippocampal but not serum cytokine levels are altered by traffic-related air pollution in TgF344-AD and wildtype Fischer 344 rats in a sex-and age-dependent …
KT Patten, AE Valenzuela, C Wallis… - Frontiers in Cellular …, 2022 - frontiersin.org
Epidemiological studies have demonstrated that air pollution is a significant risk factor for
age-related dementia, including Alzheimer's disease (AD). It has been posited that traffic …
age-related dementia, including Alzheimer's disease (AD). It has been posited that traffic …