The mammalian skeletal system is densely innervated by both neural and vascular
networks. Peripheral nerves in the skeleton include sensory and sympathetic nerves. The …

Administration of anesthetic agents fundamentally shifts the responsibility for maintenance of
homeostasis from the patient and their intrinsic physiological regulatory mechanisms to the …

Vascular tone of resistance arteries and arterioles determines peripheral vascular
resistance, contributing to the regulation of blood pressure and blood flow to, and within the …

Functional Magnetic Resonance Imaging (fMRI) studies have become increasingly popular
both with clinicians and researchers as they are capable of providing unique insights into …

It is widely known that vitamin D receptors have been found in neurons and glial cells, and
their highest expression is in the hippocampus, hypothalamus, thalamus and subcortical …

Decreased cerebrovascular blood flow and function are associated with lower cognitive
functioning and increased risk of neurodegenerative diseases. Prolonged sitting impairs …

Regulation of the cerebral circulation relies on the complex interplay between
cardiovascular, respiratory, and neural physiology. In health, these physiologic systems act …

Voxel-based physiological (VBP) variables derived from blood oxygen level dependent
(BOLD) fMRI time-course variations include: amplitude of low frequency fluctuations (ALFF) …

Vitamin D is a hormone with both genomic and non-genomic actions. It exerts its activity by
binding vitamin D receptor (VDR), which belongs to the superfamily of nuclear receptors and …

The neurovascular unit (NVU) is a dynamic center for substance exchange between the
blood and the brain, making it an essential gatekeeper for central nervous system (CNS) …