In the past two decades, major breakthroughs that improve our understanding of the
pathophysiology and therapy of kidney stones (KS) have been lacking. The disease …

Historically nephrolithiasis was considered a disease of dehydration and abnormal urine
composition. However, over the past several decades, much has been learned about the …

Results Among an at-risk population of 4,625,364 people, 152,925 unique patients received
emergency, inpatient, or surgical care for nephrolithiasis. Between 1997 and 2012, the …

The occurrence of urolithiasis in the United States has increased; however, information on
long-term trends, including recurrence rates, is lacking. Here we describe national trends in …

Purpose We review the current literature on the diagnostic evaluation and dietary and
pharmacological management of children with nephrolithiasis. Materials and Methods We …

Urinary stone disease (USD) is an increasing clinical problem in both children and adults.
One in ten individuals will experience a urinary stone, yet the mechanisms responsible for …

The incidence of adult urolithiasis has increased significantly in industrialized countries over
the past decades. Sound incidence rates are not available for children, nor are they known …

The incidence of nephrolithiasis (kidney stones) is rising worldwide, especially in women
and with increasing age. Kidney stones are associated with chronic kidney disease …

The incidence of pediatric nephrolithiasis has been steadily increasing for the past several
decades, with a concomitant concerning increase in health care costs and burden to …

Nephrolithiasis in children is a painful and costly disease that may also have detrimental
long-term effects on kidney function. Recent data provide evidence that the incidence of …