Mortality in people with schizophrenia: a systematic review and meta‐analysis of relative risk and aggravating or attenuating factors

CU Correll, M Solmi, G Croatto, LK Schneider… - World …, 2022 - Wiley Online Library
People with schizophrenia die 15‐20 years prematurely. Understanding mortality risk and
aggravating/attenuating factors is essential to reduce this gap. We conducted a systematic …

Severe Mental Illness and Cardiovascular Disease: JACC State-of-the-Art Review

M Goldfarb, M De Hert, J Detraux, K Di Palo… - Journal of the American …, 2022 - jacc.org
People with severe mental illness, consisting of schizophrenia, bipolar disorder, and major
depression, have a high burden of modifiable cardiovascular risk behaviors and conditions …

Heart-brain connections: Phenotypic and genetic insights from magnetic resonance images

B Zhao, T Li, Z Fan, Y Yang, J Shu, X Yang, X Wang… - Science, 2023 - science.org
Cardiovascular health interacts with cognitive and mental health in complex ways, yet little is
known about the phenotypic and genetic links of heart-brain systems. We quantified heart …

Peripheral levels of C-reactive protein, tumor necrosis factor-α, interleukin-6, and interleukin-1β across the mood spectrum in bipolar disorder: a meta-analysis of …

M Solmi, MS Sharma, EF Osimo, M Fornaro… - Brain, Behavior, and …, 2021 - Elsevier
Importance It is unclear whether differences exist in the magnitude and variability of pro-
inflammatory mediators in the different phases of bipolar disorder (BD) and among subjects …

Mortality gap and physical comorbidity of people with severe mental disorders: the public health scandal

A Fiorillo, N Sartorius - Annals of General Psychiatry, 2021 - Springer
Background Patients suffering from severe mental disorders, including schizophrenia, major
depression and bipolar disorders, have a reduced life expectancy compared to the general …

Disparities in screening and treatment of cardiovascular diseases in patients with mental disorders across the world: systematic review and meta-analysis of 47 …

M Solmi, J Fiedorowicz, L Poddighe… - American Journal of …, 2021 - Am Psychiatric Assoc
Objective: This study used meta-analysis to assess disparities in cardiovascular disease
(CVD) screening and treatment in people with mental disorders, a group that has elevated …

Attention‐deficit/hyperactivity disorder as a risk factor for cardiovascular diseases: A nationwide population‐based cohort study

L Li, Z Chang, J Sun, M Garcia‐Argibay… - World …, 2022 - Wiley Online Library
Accumulating evidence suggests a higher risk for cardiovascular diseases among
individuals with mental disorders, but very little is known about the risk for overall and …

Efficient model for coronary artery disease diagnosis: a comparative study of several machine learning algorithms

A Garavand, C Salehnasab… - Journal of …, 2022 - Wiley Online Library
Background. In today's industrialized world, coronary artery disease (CAD) is one of the
leading causes of death, and early detection and timely intervention can prevent many of its …

Risk factors for clozapine‐induced myocarditis and cardiomyopathy: A systematic review and meta‐analysis

M Vickers, V Ramineni, E Malacova… - Acta Psychiatrica …, 2022 - Wiley Online Library
Objective Clozapine is the most effective medication for treatment‐refractory schizophrenia,
but it is associated with severe cardiac adverse events including myocarditis and …

Use of low‐dose quetiapine increases the risk of major adverse cardiovascular events: results from a nationwide active comparator‐controlled cohort study

M Højlund, K Andersen, MT Ernst, CU Correll… - World …, 2022 - Wiley Online Library
At standard doses used for schizophrenia or bipolar disorder, quetiapine has been
associated with weight gain and increased levels of triglycerides, total cholesterol and low …