Medicine-based evidence in congenital heart disease: how artificial intelligence can guide treatment decisions for individual patients

J Van den Eynde, C Manlhiot… - Frontiers in …, 2021 - frontiersin.org
Built on the foundation of the randomized controlled trial (RCT), Evidence Based Medicine
(EBM) is at its best when optimizing outcomes for homogeneous cohorts of patients like …

The fluidity of biosocial identity and the effects of place, space, and time

D Wiese, JR Escobar, Y Hsu, RJ Kulathinal… - Social science & …, 2018 - Elsevier
Public and scientific conceptions of identity are changing alongside advances in
biotechnology, with important relevance to health and medicine. In particular, biological …

Removing the mask of average treatment effects in chronic Lyme disease research using big data and subgroup analysis

L Johnson, M Shapiro, J Mankoff - Healthcare, 2018 - mdpi.com
Lyme disease is caused by the bacteria borrelia burgdorferi and is spread primarily through
the bite of a tick. There is considerable uncertainty in the medical community regarding the …

Comorbidity: from a confounder in longitudinal clinical research to the main issue in population management

ME Charlson, MT Wells - Psychotherapy and psychosomatics, 2022 - karger.com
In his recent editorial “Forty Years of Clinimetrics,” Fava eloquently summarized the
contribution of clinimetrics to moving clinical science from a focus on diagnosis and …

The biological and biographical basis of precision medicine

G Lobitz, K Armstrong, J Concato, BH Singer… - Psychotherapy and …, 2019 - karger.com
Construction of a patient narrative (case history) is a core strategy in the care of patients.
Recent advances in biomarker identification and digital sensors to monitor physiological and …

[HTML][HTML] A patient similarity network (CHDmap) to predict outcomes after congenital heart surgery: development and validation study

H Li, M Zhou, Y Sun, J Yang, X Zeng… - JMIR Medical …, 2024 - medinform.jmir.org
Background Although evidence-based medicine proposes personalized care that considers
the best evidence, it still fails to address personal treatment in many real clinical scenarios …

Pharmacogenomic phase transition from personalized medicine to patient-centric customized delivery

A Radhakrishnan, G Kuppusamy… - The …, 2020 - nature.com
Personalized medicine has been a booming area in clinical research for the past decade, in
which the detailed information about the patient genotype and clinical conditions were …

Precision oncology by point-of-care therapeutic drug monitoring and dosage adjustment of conventional cytotoxic chemotherapies: a perspective

M Briki, P André, Y Thoma, N Widmer, AD Wagner… - Pharmaceutics, 2023 - mdpi.com
Therapeutic drug monitoring (TDM) of conventional cytotoxic chemotherapies is strongly
supported yet poorly implemented in daily practice in hospitals. Analytical methods for the …

[Retracted] Construction of Clinical Pathway Information Management System under the Guidance of Evidence‐Based Medicine

X Wang, J Chen, F Peng, J Lu - Journal of Healthcare …, 2021 - Wiley Online Library
This study focuses on clinical pathways guided by evidence‐based medicine (EBM). With
the clinical pathway as the center, the subjective and objective medical knowledge of …

Telestroke: barriers to the transition

C Busti, A Gamboni, G Calabrò, M Zampolini… - Frontiers in …, 2021 - frontiersin.org
Only few patients affected by acute stroke are treated with thrombolytic therapy or
endovascular treatment, especially in rural or underserved areas/hospitals. A survey of …