Oxidative stress has been implicated in a wide range of pathological conditions. The
transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) exerts a central role in …

The phrase “Let food be thy medicine…” means that food can be a form of medicine and
medicine can be a form of food; in other words, that the diet we eat can have a significant …

Eighteen novel functionalized phenyl acetate derivatives of benzo [e]-bispyrone fused
hybrids and their three precursors are developed in this study. The precursor acetic acid …

Introduction The nuclear factor erythroid 2-related factor 2 (Nrf2) is a pivotal transcription
factor that controls the expression of numerous cytoprotective genes and regulates cellular …

Several nitrogen heterocyclic analogues have been applied to clinical practice, and about
75% of drugs approved by the FDA contain at least a heterocyclic moiety. Thus, nitrogen …

In the current study, the phytochemical constituents of volatile organic compounds (VOCs)
obtained from Sida rhombifolia L. were identified by GC-FID and GC-MS analysis. A total of …

Keap1 (Kelch-like ECH-associated protein 1) is one of the major negative regulators of the
transcription factor Nrf2 (nuclear factor erythroid-2-related factor 2), which induces the …

Quercetin oxidation leads to the formation of a metabolite, 2-(3, 4-dihydroxybenzoyl)-2, 4, 6-
trihydroxy-3 (2H)-benzofuranone, whose antioxidant potency was recently reported to be a …

Mutations in metabolic enzymes are associated with hereditary and sporadic forms of
cancer. For example, loss-of-function mutations affecting fumarate hydratase (FH), the …

Phenothiazines (PTZs) are an emerging group of molecules showing effectiveness toward
redox signaling and reduction of oxidative injury to cells, via the activation on Kelch‐like …