Major depressive disorder

W Marx, BWJH Penninx, M Solmi… - Nature Reviews …, 2023 - nature.com
Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …

[HTML][HTML] The microbiota–gut–brain Axis in psychiatric disorders

A Góralczyk-Bińkowska, D Szmajda-Krygier… - International journal of …, 2022 - mdpi.com
Modulating the gut microbiome and its influence on human health is the subject of intense
research. The gut microbiota could be associated not only with gastroenterological diseases …

[HTML][HTML] Critical windows of early-life microbiota disruption on behaviour, neuroimmune function, and neurodevelopment

CMK Lynch, CSM Cowan, TFS Bastiaanssen… - Brain, Behavior, and …, 2023 - Elsevier
Numerous studies have emphasised the importance of the gut microbiota during early life
and its role in modulating neurodevelopment and behaviour. Epidemiological studies have …

Interactions between gut microbiota and polyphenols: A mechanistic and metabolomic review

H Cheng, D Zhang, J Wu, J Liu, Y Zhou, Y Tan, W Feng… - Phytomedicine, 2023 - Elsevier
Background Polyphenols are a class of naturally sourced compounds with widespread
distribution and an extensive array of bioactivities. However, due to their complex …

[HTML][HTML] Mechanisms of blood–brain barrier protection by microbiota-derived short-chain fatty acids

E Fock, R Parnova - Cells, 2023 - mdpi.com
Impairment of the blood–brain barrier (BBB) integrity is implicated in the numerous
neurological disorders associated with neuroinflammation, neurodegeneration and aging. It …

The double-edged sword of probiotic supplementation on gut microbiota structure in Helicobacter pylori management

A Nabavi-Rad, A Sadeghi, H Asadzadeh Aghdaei… - Gut …, 2022 - Taylor & Francis
As Helicobacter pylori management has become more challenging and less efficient over
the last decade, the interest in innovative interventions is growing by the day. Probiotic co …

Pesticide exposure and the microbiota-gut-brain axis

R Matsuzaki, E Gunnigle, V Geissen, G Clarke… - The ISME …, 2023 - academic.oup.com
The gut microbiota exist within a dynamic ecosystem shaped by various factors that includes
exposure to xenobiotics such as pesticides. It is widely regarded that the gut microbiota …

Antibiotics and mental health: The good, the bad and the ugly

K Dinan, T Dinan - Journal of Internal Medicine, 2022 - Wiley Online Library
Antibiotics are recognised as, on occasion, producing psychiatric side effects, most notably
depression and anxiety. Apart from antimicrobial activity, antibiotics have multiple off‐target …

[HTML][HTML] Decoding the neurocircuitry of gut feelings: region-specific microbiome-mediated brain alterations

BL Sharvin, MR Aburto, JF Cryan - Neurobiology of Disease, 2023 - Elsevier
Research in the last decade has unveiled a crucial role for the trillions of microorganisms
that reside in the gut in influencing host neurodevelopment across the lifespan via the …

[HTML][HTML] Diet and the microbiota–gut–brain-axis: a primer for clinical nutrition

G Ribeiro, A Ferri, G Clarke… - Current Opinion in Clinical …, 2022 - journals.lww.com
Findings in diet–microbiome–brain studies can have groundbreaking implications in clinical
nutrition practice and research. Modulating brain processes through diet via the gut …