Nano-enhanced immunotherapy: Targeting the immunosuppressive tumor microenvironment

Y Jin, Y Huang, H Ren, H Huang, C Lai, W Wang… - Biomaterials, 2024 - Elsevier
The tumor microenvironment (TME), which is mostly composed of tumor cells, immune cells,
signaling molecules, stromal tissue, and the vascular system, is an integrated system that is …

[HTML][HTML] Mitochondrial transplantation as a novel therapeutic strategy for cardiovascular diseases

M Sun, W Jiang, N Mu, Z Zhang, L Yu, H Ma - Journal of Translational …, 2023 - Springer
Cardiovascular disease (CVD) is the leading cause of noncommunicable disease-related
death worldwide, and effective therapeutic strategies against CVD are urgently needed …

[HTML][HTML] Albumin is a component of the esterase status of human blood plasma

DA Belinskaia, PA Voronina, PI Popova… - International Journal of …, 2023 - mdpi.com
The esterase status of blood plasma can claim to be one of the universal markers of various
diseases; therefore, it deserves attention when searching for markers of the severity of …

[HTML][HTML] Beyond protein synthesis: the emerging role of arginine in poultry nutrition and host-microbe interactions

S Fathima, WG Al Hakeem, RK Selvaraj… - Frontiers in …, 2024 - frontiersin.org
Arginine is a functional amino acid essential for various physiological processes in poultry.
The dietary essentiality of arginine in poultry stems from the absence of the enzyme …

[HTML][HTML] Aberrant hyper-expression of the RNA binding protein GIGYF2 in endothelial cells modulates vascular aging and function

F Niu, Z Li, Y Ren, Z Li, H Guan, Y Li, Y Zhang, Y Li… - Redox Biology, 2023 - Elsevier
Vascular endothelial cells (ECs) senescence plays a crucial role in vascular aging that
promotes the initiation and progression of cardiovascular disease. The mutation of Grb10 …

Nitric Oxide Signaling and Regulation in the Cardiovascular System: Recent Advances

M Carlstrom, E Weitzberg, JO Lundberg - Pharmacological Reviews, 2024 - ASPET
Nitric oxide (NO) from endothelial NO synthase (eNOS) importantly contributes to vascular
homeostasis. Reduced NO production or increased scavenging during disease conditions …

Regulatory effects of curcumin on nitric oxide signaling in the cardiovascular system

S Abolfazli, P Mortazavi, A Kheirandish, AE Butler… - Nitric Oxide, 2023 - Elsevier
The continuously rising prevalence of cardiovascular disease (CVD) globally substantially
impacts the economic growth of developing countries. Indeed, one of the leading causes of …

Novel orally bioavailable piperidine derivatives as extracellular arginase inhibitors developed by a ring expansion

A Gzik, B Borek, J Chrzanowski, K Jedrzejczak… - European Journal of …, 2024 - Elsevier
Arginase is a multifaced enzyme that plays an important role in health and disease being
regarded as a therapeutic target for the treatment of various pathological states such as …

[HTML][HTML] Management of the Brain: Essential Oils as Promising Neuroinflammation Modulator in Neurodegenerative Diseases

R Avola, AG Furnari, ACE Graziano, A Russo… - Antioxidants, 2024 - mdpi.com
Neuroinflammation, a pivotal factor in the pathogenesis of various brain disorders, including
neurodegenerative diseases, has become a focal point for therapeutic exploration. This …

Biodegradation of ochratoxin A by Brevundimonas diminuta HAU429: Characterized performance, toxicity evaluation and functional enzymes

L Zhang, X Zhang, X Chen, W Zhang, L Zhao… - Food Research …, 2024 - Elsevier
Ochratoxin A (OTA) is a notorious mycotoxin commonly contaminating food products
worldwide. In this study, an OTA-degrading strain Brevundimonas diminuta HAU429 was …