HIV infection progressively weakens the immune system by infecting and destroying cells
involved in host defense. Viral infection symptoms are generated and aggravated as …

Leishmaniasis is a complex infectious parasitic disease caused by protozoa of the genus
Leishmania, belonging to a group of neglected tropical diseases. It establishes significant …

Vaccines against parasites have lagged centuries behind those against viral and bacterial
infections, despite the devastating morbidity and widespread effects of parasitic diseases …

Despite decades of research devoted to finding a vaccine against leishmaniasis, we are still
lacking a safe and effective vaccine for humans. Given this scenario, the search for a new …

The lack of safe and cost-effective treatments against leishmaniasis highlights the urgent
need to develop improved leishmanicidal agents. Antimicrobial peptides (AMPs) are an …

The protozoan parasite Leishmania donovani, residing and replicating within the cells of the
monocyte-macrophage (mono-mac) lineage, causes visceral leishmaniasis (VL) in humans …

Leishmaniasis is a vector-borne disease caused by obligate intracellular protozoan
parasites that can infect humans and other mammals. Pro-and anti-inflammatory cytokines …

Most of the existing Leishmania-related research about TLR-2 agonists was focusing on
their role as adjuvants in the vaccine, few studied its therapeutic effect. This paper aims to …

A study was conducted on BALB/c mice infected with Leishmania (Leishmania)
amazonensis to analyse the effects of 0.5% miltefosine (MTF) hydrogel treatment on …

Chemokines belong to the group of small proteins within the cytokine family having strong
chemo-attractant properties. In most cases, the strong immuno-modulatory role of …