Intervertebral disc degeneration (IVDD) is a main cause of low back pain (LBP), which can
lead to disability and thus generate a heavy burden on society. IVDD is characterized by a …

The field of cell death has witnessed significant advancements since the initial discovery of
apoptosis in the 1970s. This review delves into the intricacies of pyroptosis, a more recently …

Glioma is the most common primary malignant tumor in the central nervous system.
Disulfidptosis is a recently identified programmed cell death in tumor cells overexpressing …

The heightened risk of ionizing radiation exposure, stemming from radiation accidents and
potential acts of terrorism, has spurred growing interests in devising effective …

Pyroptosis, an inflammatory programmed cell death, distinguishes itself from apoptosis and
necroptosis and has drawn increasing attention. Recent studies have revealed a correlation …

Nanoliposomes have a broad range of applications in the treatment of autoimmune
inflammatory diseases because of their ability to considerably enhance drug transport. For …

Cardiovascular disease is the leading cause of death worldwide, and it commonly results
from atherosclerotic plaque progression. One of the increasingly recognized drivers of …

Background Pulmonary hypertension (PH) is a complex vascular disorder, characterized by
pulmonary vessel remodeling and perivascular inflammation. Pulmonary arterial smooth …

The gasdermin (GSDM) family has garnered significant attention for its pivotal role in
immunity and disease as a key player in pyroptosis. This recently characterized class of pore …

Endometriosis (EMS) is known to be closely associated with inflammation. We evaluate the
possible mechanism linking the PI3K/AKT signaling pathway with pyroptosis and …