Advancements in antimicrobial nanoscale materials and self-assembling systems

JA Doolan, GT Williams, KLF Hilton… - Chemical Society …, 2022 - pubs.rsc.org
Antimicrobial resistance is directly responsible for more deaths per year than either
HIV/AIDS or malaria and is predicted to incur a cumulative societal financial burden of at …

[HTML][HTML] Functional hydrogels for diabetic wound management

D Gao, Y Zhang, DT Bowers, W Liu, M Ma - APL bioengineering, 2021 - pubs.aip.org
Diabetic wounds often have a slow healing process and become easily infected owing to
hyperglycemia in wound beds. Once planktonic bacterial cells develop into biofilms, the …

Advances in the sensing and treatment of wound biofilms

S Darvishi, S Tavakoli, M Kharaziha… - Angewandte …, 2022 - Wiley Online Library
Wound biofilms represent a particularly challenging problem in modern medicine. They are
increasingly antibiotic resistant and can prevent the healing of chronic wounds. However …

What makes wounds chronic

SR Goldberg, RF Diegelmann - Surgical Clinics, 2020 - surgical.theclinics.com
The wound healing process consists of a carefully coordinated sequence of events after a
cutaneous injury leading to regeneration of the skin protective barrier. 1 After an initial insult …

ZnO nanoparticles-modified dressings to inhibit wound pathogens

SMI Rayyif, HB Mohammed, C Curuțiu, AC Bîrcă… - Materials, 2021 - mdpi.com
Zinc oxide (ZnO) nanoparticles (NPs) have been investigated for various skin therapies in
recent years. These NPs can improve the healing and modulate inflammation in the wounds …

Challenges and innovations in treating chronic and acute wound infections: from basic science to clinical practice

X Ding, Q Tang, Z Xu, Y Xu, H Zhang, D Zheng… - Burns & …, 2022 - academic.oup.com
Acute and chronic wound infection has become a major worldwide healthcare burden
leading to significantly high morbidity and mortality. The underlying mechanism of infections …

Pharmacological activation of Nrf2 promotes wound healing

P Victor, D Sarada, KM Ramkumar - European journal of pharmacology, 2020 - Elsevier
Wound repair and regeneration is a complex orchestrated process, comprising several
phases interconnecting various cellular events and triggering multiple intracellular …

Chronic wound dressings–pathogenic bacteria anti-biofilm treatment with bacterial cellulose-chitosan polymer or bacterial cellulose-chitosan dots composite …

DZ Zmejkoski, NM Zdravković, DD Trišić… - International Journal of …, 2021 - Elsevier
Since the pathogenic bacteria biofilms are involved in 70% of chronic infections and their
resistance to antibiotics is increased, the research in this field requires new healing agents …

Biofilms in chronic wound infections: innovative antimicrobial approaches using the in vitro Lubbock chronic wound biofilm model

F Diban, S Di Lodovico, P Di Fermo, S D'Ercole… - International journal of …, 2023 - mdpi.com
Chronic wounds have harmful effects on both patients and healthcare systems. Wound
chronicity is attributed to an impaired healing process due to several host and local factors …

Signaling pathways associated with chronic wound progression: A systems biology approach

P Basu, M Martins-Green - Antioxidants, 2022 - mdpi.com
Previously we have shown that several oxidative stress-driven pathways in cutaneous
chronic wounds are dysregulated in the first 48 h post-wounding. Here, we performed an …