Diabetic vascular diseases: molecular mechanisms and therapeutic strategies

Y Li, Y Liu, S Liu, M Gao, W Wang, K Chen… - Signal transduction and …, 2023 - nature.com
Vascular complications of diabetes pose a severe threat to human health. Prevention and
treatment protocols based on a single vascular complication are no longer suitable for the …

Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress‐and aging‐related diseases

AG Panossian, T Efferth, AN Shikov… - Medicinal research …, 2021 - Wiley Online Library
Adaptogens comprise a category of herbal medicinal and nutritional products promoting
adaptability, resilience, and survival of living organisms in stress. The aim of this review was …

Thermosensitive hydrogel incorporating Prussian blue nanoparticles promotes diabetic wound healing via ROS scavenging and mitochondrial function restoration

Z Xu, Y Liu, R Ma, J Chen, J Qiu, S Du… - … applied materials & …, 2022 - ACS Publications
Diabetic foot ulcer is a serious complication in diabetes patients, imposing a serious
physical and economic burden to patients and to the healthcare system as a whole …

Insights into SGLT2 inhibitor treatment of diabetic cardiomyopathy: focus on the mechanisms

K Huang, X Luo, B Liao, G Li, J Feng - Cardiovascular Diabetology, 2023 - Springer
Among the complications of diabetes, cardiovascular events and cardiac insufficiency are
considered two of the most important causes of death. Experimental and clinical evidence …

Plant-microbial interaction: The mechanism and the application of microbial elicitor induced secondary metabolites biosynthesis in medicinal plants

I Chamkhi, T Benali, T Aanniz, N El Menyiy… - Plant Physiology and …, 2021 - Elsevier
Plants and microbes interact with each other via different chemical signaling pathways. At
the risophere level, the microbes can secrete molecules, called elicitors, which act on their …

Dapagliflozin restores impaired autophagy and suppresses inflammation in high glucose-treated HK-2 cells

J Xu, M Kitada, Y Ogura, H Liu, D Koya - Cells, 2021 - mdpi.com
Sodium-glucose cotransporter2 (SGLT2) inhibitors have a reno-protective effect in diabetic
kidney disease. However, the detailed mechanism remains unclear. In this study, human …

Cereal polyphenols inhibition mechanisms on advanced glycation end products and regulation on type 2 diabetes

L Dong, Y Li, Q Chen, Y Liu, Z Wu, D Pan… - Critical Reviews in …, 2023 - Taylor & Francis
Advanced glycation end products (AGEs), the products of non-enzymatic browning reactions
between the active carbonyl groups of reducing sugars and the free amines of amino acids …

Salidroside, a phenyl ethanol glycoside from Rhodiola crenulata, orchestrates hypoxic mitochondrial dynamics homeostasis by stimulating Sirt1/p53/Drp1 signaling

X Wang, Y Tang, N Xie, J Bai, S Jiang, Y Zhang… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Rhodiola crenulata is clinically used to combat hypobaric
hypoxia brain injury at high altitude with the function of invigorating Qi and promoting blood …

Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota

Y Zhao, X Liu, Y Zheng, W Liu, C Ding - Scientific reports, 2021 - nature.com
Aronia melanocarpa is a natural medicinal plant that has a variety of biological activities, its
fruit is often used for food and medicine. Aronia melanocarpa polysaccharide (AMP) is the …

The role of adaptogens in prophylaxis and treatment of viral respiratory infections

A Panossian, T Brendler - Pharmaceuticals, 2020 - mdpi.com
The aim of our review is to demonstrate the potential of herbal preparations, specifically
adaptogens for prevention and treatment of respiratory infections, as well as convalescence …