Helicobacter pylori infection, its laboratory diagnosis, and antimicrobial resistance: a perspective of clinical relevance

S Ansari, Y Yamaoka - Clinical microbiology reviews, 2022 - Am Soc Microbiol
Despite the recent decrease in overall prevalence of Helicobacter pylori infection, morbidity
and mortality rates associated with gastric cancer remain high. The antimicrobial resistance …

[HTML][HTML] Review of current diagnostic methods and advances in Helicobacter pylori diagnostics in the era of next generation sequencing

D Pohl, PM Keller, V Bordier… - World journal of …, 2019 - ncbi.nlm.nih.gov
Helicobacter pylori (H. pylori) infection is highly prevalent in the human population and may
lead to severe gastrointestinal pathology including gastric and duodenal ulcers, mucosa …

Antibiotic resistance in Helicobacter pylori

C Alba, A Blanco, T Alarcón - Current opinion in infectious …, 2017 - journals.lww.com
Metronidazole and clarithromycin resistance rates are alarming although they vary among
populations. Tetracycline and amoxicillin-resistance are very low in most countries. H. pylori …

Antibiotic Resistance, Susceptibility Testing and Stewardship in Helicobacter pylori Infection

HY Ng, WK Leung, KS Cheung - International Journal of Molecular …, 2023 - mdpi.com
Despite the declining trend of Helicobacter pylori (H. pylori) prevalence around the globe,
ongoing efforts are still needed to optimize current and future regimens in view of the …

Antimicrobial resistance patterns and genetic elements associated with the antibiotic resistance of Helicobacter pylori strains from Shanghai

Y Liu, S Wang, F Yang, W Chi, L Ding, T Liu, F Zhu, D Ji… - Gut pathogens, 2022 - Springer
Abstract Background Shanghai, in east China, has one of the world's highest burdens of
Helicobacter pylori infection. While multidrug regimens can effectively eradicate H. pylori …

Biomarker Characterization and Prediction of Virulence and Antibiotic Resistance from Helicobacter pylori Next Generation Sequencing Data

JS Vital, L Tanoeiro, R Lopes-Oliveira, FF Vale - Biomolecules, 2022 - mdpi.com
The Gram-negative bacterium Helicobacter pylori colonizes ca 50% of human stomachs
worldwide and is the major risk factor for gastric adenocarcinoma. Its high genetic variability …

[HTML][HTML] Biofilm of Helicobacter pylori: Life cycle, features, and treatment options

Y Elshenawi, S Hu, S Hathroubi - Antibiotics, 2023 - mdpi.com
Helicobacter pylori is a gastric pathogen that infects nearly half of the global population and
is recognized as a group 1 carcinogen by the Word Health Organization. The global rise in …

The prevalence of clarithromycin-resistant Helicobacter pylori isolates: a systematic review and meta-analysis

M Sholeh, S Khoshnood, T Azimi, J Mohamadi… - PeerJ, 2023 - peerj.com
Background Knowledge of global clarithromycin (CLA)-resistant rates of Helicobacter pylori
(H. pylori) is crucial for decision of the most appropriate eradication therapies with good …

Resistance mechanisms of Helicobacter pylori and its dual target precise therapy

Y Gong, Y Yuan - Critical reviews in microbiology, 2018 - Taylor & Francis
Helicobacter pylori drug resistance presents a significant challenge to the successful
eradication of this pathogen. To find strategies to improve the eradication efficacy of H …

High Prevalence of Antibiotic Resistance in Iranian Helicobacter pylori Isolates: Importance of Functional and Mutational Analysis of Resistance Genes and Virulence …

N Farzi, A Yadegar, A Sadeghi… - Journal of clinical …, 2019 - mdpi.com
The high prevalence of antibiotic resistance in Helicobacter pylori has become a great
challenge in Iran. The genetic mutations that contribute to the resistance have yet to be …