Outcomes and endpoints in cancer trials: bridging the divide
MK Wilson, D Collyar, DT Chingos… - The lancet …, 2015 - thelancet.com
Cancer is not one disease. Outcomes and endpoints in trials should incorporate the
therapeutic modality and cancer type because these factors affect clinician and patient …
therapeutic modality and cancer type because these factors affect clinician and patient …
Stakeholder engagement in HIV cure research: lessons learned from other HIV interventions and the way forward
YR Lo, C Chu, J Ananworanich, JL Excler… - AIDS Patient Care and …, 2015 - liebertpub.com
Clinical and basic science advances have raised considerable hope for achieving an HIV
cure by accelerating research. This research is dominated primarily by issues about the …
cure by accelerating research. This research is dominated primarily by issues about the …
[PDF][PDF] Ethics as governance in genomics and beyond
The Human Genome Project (HGP) is often described as the first large-scale scientific
project to incorporate investigation of its own ethical and social dimensions into the “core” …
project to incorporate investigation of its own ethical and social dimensions into the “core” …
Genetic research on alcohol use outcomes in African American populations: A review of the literature, associated challenges, and implications
Background and Objectives There have been remarkable advances in understanding
genetic influences on complex traits; however, individuals of African descent have been …
genetic influences on complex traits; however, individuals of African descent have been …
Navigating social and ethical challenges of biobanking for human microbiome research
Background Biobanks are considered to be key infrastructures for research development
and have generated a lot of debate about their ethical, legal and social implications (ELSI) …
and have generated a lot of debate about their ethical, legal and social implications (ELSI) …
Ethical challenges of germline genetic enhancement
The new reproductive technologies have opened the door to different processes of germline
genetic enhancement by which the characteristics of an individual according to the interests …
genetic enhancement by which the characteristics of an individual according to the interests …
[HTML][HTML] The translational potential of research on the ethical, legal, and social implications of genomics
W Burke, P Appelbaum, L Dame, P Marshall… - Genetics in …, 2015 - Elsevier
Federally funded research on the ethical, legal, and social implications (ELSI) of genomics
includes a programmatic charge to consider policy-relevant questions and to communicate …
includes a programmatic charge to consider policy-relevant questions and to communicate …
Applying a risk governance approach to examine how professionals perceive the benefits and risks of clinical genomics in Australian healthcare
Clinical genomics is a system of multiple stakeholders and institutions. Yet, studies focusing
on the comparative perspectives of these stakeholders are limited. This study engages four …
on the comparative perspectives of these stakeholders are limited. This study engages four …
How biomedical HIV prevention trials incorporate behavioral and social sciences research: a typology of approaches
In the field of biomedical HIV prevention, researchers have meaningfully incorporated
behavioral and social sciences research (BSSR) into numerous clinical trials, though the …
behavioral and social sciences research (BSSR) into numerous clinical trials, though the …
Community perspectives on communicating about precision medicine in an Alaska native tribal health care system
RB Woodbury, JA Beans, KA Wark, P Spicer… - Frontiers in …, 2020 - frontiersin.org
Background: Precision medicine seeks to better tailor medical care to the needs of individual
patients, but there are challenges involved in communicating to patients, health care …
patients, but there are challenges involved in communicating to patients, health care …