Multidrug resistance (MDR): A widespread phenomenon in pharmacological therapies

A Catalano, D Iacopetta, J Ceramella, D Scumaci… - Molecules, 2022 - mdpi.com
Multidrug resistance is a leading concern in public health. It describes a complex phenotype
whose predominant feature is resistance to a wide range of structurally unrelated cytotoxic …

Natural products as anticancer agents: current status and future perspectives

A Naeem, P Hu, M Yang, J Zhang, Y Liu, W Zhu… - Molecules, 2022 - mdpi.com
Natural products have been an invaluable and useful source of anticancer agents over the
years. Several compounds have been synthesized from natural products by modifying their …

Emerging carbon-supported single-atom catalysts for biomedical applications

G Liao, L Zhang, C Li, SY Liu, B Fang, H Yang - Matter, 2022 - cell.com
Carbon-supported single-atom catalysts (SACs) are very promising for biomedical
applications due to their unique superiorities, including uniform size in nanoscale, ease of …

Recent advancements in the targeted delivery of etoposide nanomedicine for cancer therapy: A comprehensive review

S Fathi-Karkan, R Arshad, A Rahdar… - European Journal of …, 2023 - Elsevier
Etoposide (ETO), a popular anticancer drug that inhibits topoisomerase II enzymes, may be
administered more effectively and efficiently due to nanomedicine. The therapeutic …

Porphyrin‐based Covalent organic framework for imaging‐guided cancer Combinatorial Immuno‐sonodynamic therapy

Z Lu, S Bai, Y Jiang, S Wu, D Xu, Y Chen… - Advanced Functional …, 2022 - Wiley Online Library
The rational design of tumor microenvironment (TME)‐activated nanomedicine is driving a
new direction in tumor immunology. Furthermore, the novel therapeutic mode of ultrasound …

The development and progress of nanomedicine for esophageal cancer diagnosis and treatment

X Li, L Chen, S Luan, J Zhou, X Xiao, Y Yang… - Seminars in cancer …, 2022 - Elsevier
Esophageal cancer (EC) is a common gastrointestinal malignancy with poor prognosis and
high mortality. Although combined therapeutic strategies have been developed, the 5-year …

Transcytosis-enabled active extravasation of tumor nanomedicine

Q Zhou, J Li, J Xiang, S Shao, Z Zhou, J Tang… - Advanced Drug Delivery …, 2022 - Elsevier
Extravasation is the first step for nanomedicines in circulation to reach targeted solid tumors.
Traditional nanomedicines have been designed to extravasate into tumor interstitium …

Nanomedicine combats drug resistance in lung cancer

X Zheng, X Song, G Zhu, D Pan, H Li, J Hu… - Advanced …, 2024 - Wiley Online Library
Lung cancer is the second most prevalent cancer and the leading cause of cancer‐related
death worldwide. Surgery, chemotherapy, molecular targeted therapy, immunotherapy, and …

Application prospects of triphenylphosphine-based mitochondria-targeted cancer therapy

X Cheng, D Feng, J Lv, X Cui, Y Wang, Q Wang… - Cancers, 2023 - mdpi.com
Simple Summary Although there are various treatments for tumors, chemotherapy is still one
of the most dominant and irreplaceable treatment modalities nowadays. Unfortunately …

[HTML][HTML] Targeted drug delivery systems for elemene in cancer therapy: The story thus far

H Tian, F Zhao, Q Qi, B Yue, B Zhai - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Elemene (ELE) is a group of broad-spectrum anticancer active ingredients with low toxicity
extracted from traditional Chinese medicines (TCMs), such as Curcumae Rhizoma and …