Asthma is a chronic inflammatory disease characterized by bronchial hyperresponsiveness,
mucus overproduction and airway remodeling. Notably, we have recently demonstrated that …

The forkhead box transcription factor FoxM1, a positive regulator of the cell cycle, is required
for β-cell mass expansion postnatally, during pregnancy, and after partial pancreatectomy …

Allergic enteritis (AE) is a gastrointestinal form of food allergy. This study aimed to elucidate
cellular and molecular mechanisms of AE using a murine model. To induce AE, BALB/c wild …

The lung is susceptible to damage from a variety of sources throughout development and in
adulthood. As a result, the lung has great capacities for repair and regeneration, directed by …

Published studies with transgenic mice convincingly showed that Forkhead Box transcription
factor M1 (FOXM1) transcription factor is an important component of the KRAS/ERK …

Functional abnormal airway epithelial cells, along with activated inflammatory cells, resulting
in chronic airway inflammation, are considered as the characteristic of asthma. Fatty Acid …

Background Mouse models are useful for studying cigarette smoke (CS)-induced chronic
pulmonary pathologies such as lung emphysema. To enhance translation of large-scale …

Abstract Objective Streptococcus pneumoniae (Spn) is a common pathogen for pediatric
pneumonia and leads to severe lung injury. This study is conducted to analyze the role of F …

Crohn's disease (CD) is a type of inflammatory bowel disease that cannot be fully cured by
medication or surgery. In the present study, the aim was to understand the underlying …

As part of an ongoing search for active compounds against pulmonary inflammation, a
polyacetylene was isolated from Dendropanax morbifera leaves. The polyacetylene (9Z …