We have conducted a segregation analysis in order to characterise the transmission of
Behçet Disease (BD), a multifactorial condition with a strong genetic component. Complete …

Vascular endothelial growth factor (VEGF) is important for angiogenesis and inflammation,
both of which are codependent and contribute to the pathophysiology of Behcet disease …

Objectives. Case reports on monozygotic (MZ) twins with Behçet's syndrome (BS) have been
few and we are not aware of formal twin studies. We sought the frequency of MZ and …

Background: The term genetic anticipation is used when genetically transmitted disease
manifests at increasingly younger ages with each succeeding generation: that is, if the …

Objective: To review Behçet's disease and to describe its clinical features in the head, neck
and upper respiratory tract. Method: A literature review was undertaken, following a Medline …

Adamanitiades-Behcet's disease (ABD) is a relapsing systemic vasculitis that may involve
the eyes, skin, and almost all other organ systems. Current research on the pathogenesis of …

To investigate whether single nucleotide polymorphisms (SNPs) of the Tumor Necrosis
Factor Superfamily 4 (TNFSF4) gene are associated with Vogt–Koyanagi–Harada (VKH) …

Behçet's disease (BD) is a multisystemic vasculitis syndrome characterized by a course of
remissions and exacerbations of unpredictable frequency and duration. The disease has a …

The pathogenesis of Behçet's disease (BD) and polyarteritis nodosa (PAN) is not yet well
established. Endothelial cells have been shown to express chemokines that are involved in …

Objective. Patient-reported outcomes are increasingly accepted to be major domains in
chronic disorders. The aim of this study was to develop a patientderived disease activity …