The existing vaccine paradigm assumes that vaccines only protect against the target
infection, that effective vaccines reduce mortality corresponding to the target infection's …

Malaria is the most deadly parasitic disease, affecting hundreds of millions of people
worldwide. Malaria parasites have been associated with their hosts for millions of years …

Background Malaria is widespread in Ethiopia and has been a major cause of illness and
death in that country. Therefore, Ethiopia has been exerting enormous efforts towards …

In October, 2021, WHO recommended that the RTS, S malaria vaccine, with its strong safety
profile and high impact, be provided to children from age 5 months in regions with moderate …

Adjuvant Systems (AS) are combinations of immune stimulants that enhance the immune
response to vaccine antigens. The first vaccine containing an AS (AS04) was licensed in …

Malaria was estimated to result in 214 million clinical cases and 438,000 deaths in 2015,
primarily in children under 5 years of age. In Africa, malaria causes approximately 10% of all …

Live-attenuated measles virus (MeV) has been extraordinarily effective in preventing
measles infections and their often deadly sequelae, accompanied by remarkable safety and …

Contrary to the long-held belief that the effects of vaccines are specific for the disease they
were created; compelling evidence has demonstrated that vaccines can exert positive or …

Epidemiological observations have shown that vaccines can influence morbidity and
mortality more than can be ascribed to target-disease immunity. A growing number of …

Abstract The World Health Organisation (WHO) has recently revised how adverse events
after immunization (AEFI) are classified. Only reactions that have previously been …