A multi-institution evaluation of deformable image registration algorithms for automatic organ delineation in adaptive head and neck radiotherapy

N Hardcastle, WA Tomé, DM Cannon, CL Brouwer… - Radiation …, 2012 - Springer
Abstract Background Adaptive Radiotherapy aims to identify anatomical deviations during a
radiotherapy course and modify the treatment plan to maintain treatment objectives. This …

Evaluation of deformable image registration methods for dose monitoring in head and neck radiotherapy

B Rigaud, A Simon, J Castelli, M Gobeli… - BioMed research …, 2015 - Wiley Online Library
In the context of head and neck cancer (HNC) adaptive radiation therapy (ART), the two
purposes of the study were to compare the performance of multiple deformable image …

Adaptive radiation therapy for head and neck cancer—can an old goal evolve into a new standard?

DL Schwartz, L Dong - Journal of oncology, 2011 - Wiley Online Library
Current head and neck intensity‐modulated radiotherapy (IMRT) techniques cause
significant toxicity. This may be explained in part by the fact that IMRT cannot compensate …

Early changes in serial CBCT-measured parotid gland biomarkers predict chronic xerostomia after head and neck radiation therapy

BS Rosen, PG Hawkins, DF Polan, JM Balter… - International Journal of …, 2018 - Elsevier
Purpose To determine whether serial cone beam computed tomography (CBCT) images
taken during head and neck radiation therapy (HNR) can improve chronic xerostomia …

Accuracy of deformable image registration for contour propagation in adaptive lung radiotherapy

N Hardcastle, W Van Elmpt, D De Ruysscher… - Radiation …, 2013 - Springer
Background Deformable image registration (DIR) is an attractive method for automatic
propagation of regions of interest (ROIs) in adaptive lung radiotherapy. This study …

Performance of 12 DIR algorithms in low‐contrast regions for mass and density conserving deformation

UJ Yeo, JR Supple, ML Taylor, R Smith, T Kron… - Medical …, 2013 - Wiley Online Library
Purpose: Deformable image registration (DIR) has become a key tool for adaptive
radiotherapy to account for inter‐and intrafraction organ deformation. Of contemporary …

Randomized phase II study of physiologic MRI-directed adaptive radiation boost in poor prognosis head and neck cancer

ML Mierzwa, M Aryal, C Lee, M Schipper, M VanTil… - Clinical Cancer …, 2022 - AACR
Purpose: We conducted a randomized phase II multicenter clinical trial to test the hypothesis
that physiologic MRI-based radiotherapy (RT) dose escalation would improve the outcome …

Practical and technical key challenges in head and neck adaptive radiotherapy: The GORTEC point of view

N Delaby, A Barateau, S Chiavassa, MC Biston… - Physica Medica, 2023 - Elsevier
Anatomical variations occur during head and neck (H&N) radiotherapy (RT) treatment.
These variations may result in underdosage to the target volume or overdosage to the organ …

Quality assurance assessment of diagnostic and radiation therapy–simulation CT image registration for head and neck radiation therapy: anatomic region of interest …

ASR Mohamed, MN Ruangskul, MJ Awan, CA Baron… - Radiology, 2015 - pubs.rsna.org
Purpose To develop a quality assurance (QA) workflow by using a robust, curated, manually
segmented anatomic region-of-interest (ROI) library as a benchmark for quantitative …

The impact of robustness of deformable image registration on contour propagation and dose accumulation for head and neck adaptive radiotherapy

L Zhang, Z Wang, C Shi, T Long… - Journal of applied clinical …, 2018 - Wiley Online Library
Deformable image registration (DIR) is the key process for contour propagation and dose
accumulation in adaptive radiation therapy (ART). However, currently, ART suffers from a …