Mycobacterium tuberculosis, the leading cause of death due to infection, has a dynamic and
immunomodulatory cell envelope. The cell envelope structurally and functionally varies …

The biology of mycobacteria is dominated by a complex cell envelope of unique composition
and structure and of exceptionally low permeability. This cell envelope is the basis of many …

The success of Mycobacterium tuberculosis (Mtb) is largely attributed to its ability to
physiologically adapt and withstand diverse localized stresses within host …

Tuberculosis claims> 1 million lives annually, and its causative agent Mycobacterium
tuberculosis is a highly successful pathogen. Protein kinase B (PknB) is reported to be …

Tuberculosis (TB) is one of the primary causes of deaths due to infectious diseases. The
current TB regimen is long and complex, failing of which leads to relapse and/or the …

The Mycobacterium tuberculosis Ser/Thr protein kinases PknA and PknB are essential for
growth and have been proposed as possible drug targets. We used a titratable conditional …

Mycobacterium tuberculosis is the cause of tuberculosis (TB), a disease which continues to
overwhelm health systems in endemic regions despite the existence of effective combination …

The Mycobacterium tuberculosis protein kinase K regulates growth adaptation by facilitating
mycobacterial survival in response to a variety of in vitro and in vivo stress conditions. Here …

Virulence effectors secreted by Mycobacterium tuberculosis (Mtb) help subvert host immune
mechanisms and, therefore, are critical for establishing infection and pathogenesis …

The ability of Mycobacterium tuberculosis (Mtb) to adapt to its surrounding environment is
critical for the bacterium to successfully colonize its host. Transcriptional changes are a vital …