Abstract The 'Vascular Depression'hypothesis posits that cerebrovascular disease may
predispose, precipitate or perpetuate some geriatric depressive syndromes. This hypothesis …

In elderly people, depression mainly affects those with chronic medical illnesses and
cognitive impairment, causes suffering, family disruption, and disability, worsens the …

Backgroud Major depression is a frequent psychiatric complication among patients with
traumatic brain injury (TBI). To our knowledge, however, the clinical correlates of major …

Context Cognitive impairment in late-life depression (LLD) is highly prevalent, disabling,
poorly understood, and likely related to long-term outcome. Objectives To determine the …

Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …

Context Depression is associated with cognitive impairment and dementia. It is less clear
whether depression contributes to further cognitive decline over time, independently of …

Background A large body of research has focused on “mediating mechanisms” and
predisposing brain abnormalities to geriatric depression, but little is known about its etiology …

BACKGROUND: Executive dysfunction is common in geriatric depression and persists after
improvement of depressive symptoms. This study examined the relationship of executive …

Gray matter abnormalities within frontal–subcortical and limbic networks are hypothesized to
play a key role in the pathophysiology of late-life depression. In this work, gray matter …

Late life depression principally affects individuals with other medical and psychosocial
problems, including cognitive dysfunction, disability, medical illnesses, and social isolation …