Molecular basis and regulation of pathogenicity and patulin biosynthesis in Penicillium expansum

B Li, Y Chen, Z Zhang, G Qin, T Chen… - … Reviews in Food …, 2020 - Wiley Online Library
Penicillium expansum is a necrotrophic plant pathogen with a wide range of fruit hosts. It
causes blue mold rot during fruit storage, transport, and sale, resulting in huge economic …

Fungal evolution: cellular, genomic and metabolic complexity

MA Naranjo‐Ortiz, T Gabaldón - Biological Reviews, 2020 - Wiley Online Library
The question of how phenotypic and genomic complexity are inter‐related and how they are
shaped through evolution is a central question in biology that historically has been …

Strategies for mining fungal natural products

P Wiemann, NP Keller - Journal of Industrial Microbiology and …, 2014 - academic.oup.com
Fungi are well known for their ability to produce a multitude of natural products. On the one
hand their potential to provide beneficial antibiotics and immunosuppressants has been …

Regulatory cascade and biological activity of Beauveria bassiana oosporein that limits bacterial growth after host death

Y Fan, X Liu, NO Keyhani, G Tang… - Proceedings of the …, 2017 - National Acad Sciences
The regulatory network and biological functions of the fungal secondary metabolite
oosporein have remained obscure. Beauveria bassiana has evolved the ability to parasitize …

Molecular mechanisms of Aspergillus flavus secondary metabolism and development

MG Amare, NP Keller - Fungal Genetics and Biology, 2014 - Elsevier
The plant and human opportunistic fungus Aspergillus flavus is recognized for the
production of the carcinogen aflatoxin. Although many reviews focus on the wealth of …

Penicillium chrysogenum, a Vintage Model with a Cutting-Edge Profile in Biotechnology

F Fierro, I Vaca, NI Castillo, RO García-Rico, R Chávez - Microorganisms, 2022 - mdpi.com
The discovery of penicillin entailed a decisive breakthrough in medicine. No other medical
advance has ever had the same impact in the clinical practise. The fungus Penicillium …

[HTML][HTML] Strategies to establish the link between biosynthetic gene clusters and secondary metabolites

I Kjærbølling, UH Mortensen, T Vesth… - Fungal Genetics and …, 2019 - Elsevier
Filamentous fungi produce a vast number of bioactive secondary metabolites (SMs), some of
which have found applications in the pharmaceutical industry including as antibiotics and …

Engineering of the Filamentous Fungus Penicillium chrysogenum as Cell Factory for Natural Products

F Guzmán-Chávez, RD Zwahlen… - Frontiers in …, 2018 - frontiersin.org
Penicillium chrysogenum (renamed P. rubens) is the most studied member of a family of
more than 350 Penicillium species that constitute the genus. Since the discovery of penicillin …

Quantitative pathogenicity and host adaptation in a fungal plant pathogen revealed by whole-genome sequencing

R Amezrou, A Ducasse, J Compain, N Lapalu… - Nature …, 2024 - nature.com
Abstract Knowledge of genetic determinism and evolutionary dynamics mediating host-
pathogen interactions is essential to manage fungal plant diseases. Studies on the genetic …

One Juliet and four Romeos: VeA and its methyltransferases

Ö Sarikaya-Bayram, JM Palmer, N Keller… - Frontiers in …, 2015 - frontiersin.org
Fungal secondary metabolism has become an important research topic with great
biomedical and biotechnological value. In the postgenomic era, understanding the diversity …