[HTML][HTML] Role of lipid accumulation and inflammation in atherosclerosis: focus on molecular and cellular mechanisms

K Malekmohammad, EE Bezsonov… - Frontiers in …, 2021 - frontiersin.org
Atherosclerosis is a chronic lipid-driven and maladaptive inflammatory disease of arterial
intima. It is characterized by the dysfunction of lipid homeostasis and signaling pathways …

Atherosclerosis and inflammation: Insights from the theory of general pathological processes

E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

The role of adipokines in inflammatory mechanisms of obesity

TV Kirichenko, YV Markina, AI Bogatyreva… - International Journal of …, 2022 - mdpi.com
Adipokines are currently widely studied cellular signaling proteins produced by adipose
tissue and involved in various processes, including inflammation; energy and appetite …

Mitochondrial dysfunction in cardiovascular disease: Current status of translational research/clinical and therapeutic implications

AS Manolis, AA Manolis, TA Manolis… - Medicinal Research …, 2021 - Wiley Online Library
Mitochondria provide energy to the cell during aerobic respiration by supplying~ 95% of the
adenosine triphosphate (ATP) molecules via oxidative phosphorylation. These organelles …

Inflammatory mechanisms of diabetes and its vascular complications

LV Nedosugova, YV Markina, LA Bochkareva… - Biomedicines, 2022 - mdpi.com
The main cause of death in patients with type 2 DM is cardiovascular complications resulting
from the progression of atherosclerosis. The pathophysiology of the association between …

The role of cytokines in cholesterol accumulation in cells and atherosclerosis progression

AM Markin, YV Markina, AI Bogatyreva… - International Journal of …, 2023 - mdpi.com
Atherosclerosis is the most common cardiovascular disease and is the number one cause of
death worldwide. Today, atherosclerosis is a multifactorial chronic inflammatory disease with …

Mitochondrial dysfunction in vascular wall cells and its role in atherosclerosis

D Salnikova, V Orekhova, A Grechko… - International Journal of …, 2021 - mdpi.com
Altered mitochondrial function is currently recognized as an important factor in
atherosclerosis initiation and progression. Mitochondrial dysfunction can be caused by …

Targeting endothelial vascular cell adhesion molecule-1 in atherosclerosis: drug discovery and development of vascular cell adhesion molecule-1–directed novel …

JR Pickett, Y Wu, LF Zacchi, HT Ta - Cardiovascular Research, 2023 - academic.oup.com
Vascular cell adhesion molecule-1 (VCAM-1) has been well established as a critical
contributor to atherosclerosis and consequently as an attractive therapeutic target for anti …

Transcription factor EB regulates cardiovascular homeostasis

H Lu, J Sun, MH Hamblin, YE Chen, Y Fan - EBioMedicine, 2021 - thelancet.com
Cardiovascular diseases (CVDs) are the leading cause of death and a major cause of
disability globally. Transcription factor EB (TFEB), as a member of the microphthalmia …

Atheroprotective Effects of Glycyrrhiza glabra L.

YV Markina, TV Kirichenko, AM Markin, IY Yudina… - Molecules, 2022 - mdpi.com
Cardiovascular diseases associated with atherosclerosis are the major cause of death in
developed countries. Early prevention and treatment of atherosclerosis are considered to be …