Neurobiology of comorbid post‐traumatic stress disorder and alcohol‐use disorder
Post‐traumatic stress disorder (PTSD) and alcohol‐use disorder (AUD) are highly comorbid
in humans. Although we have some understanding of the structural and functional brain …
in humans. Although we have some understanding of the structural and functional brain …
[HTML][HTML] Understanding the neurobiological effects of drug abuse: Lessons from zebrafish models
TE Müller, BD Fontana, KT Bertoncello… - Progress in Neuro …, 2020 - Elsevier
Drug abuse and brain disorders related to drug comsumption are public health problems
with harmful individual and social consequences. The identification of therapeutic targets …
with harmful individual and social consequences. The identification of therapeutic targets …
An investigation of child maltreatment and epigenetic mechanisms of mental and physical health risk
In the present investigation, differential methylation analyses of the whole genome were
conducted among a sample of 548 school-aged low-income children (47.8% female, 67.7 …
conducted among a sample of 548 school-aged low-income children (47.8% female, 67.7 …
Childhood maltreatment severity and alcohol use in adult psychiatric inpatients: The mediating role of emotion regulation difficulties
Objective Emotion regulation difficulties are a potentially key mechanism underlying the
association between childhood maltreatment and alcohol use in adulthood. The current …
association between childhood maltreatment and alcohol use in adulthood. The current …
Genetic research on alcohol use outcomes in African American populations: A review of the literature, associated challenges, and implications
Background and Objectives There have been remarkable advances in understanding
genetic influences on complex traits; however, individuals of African descent have been …
genetic influences on complex traits; however, individuals of African descent have been …
A test of dopamine hyper-and hyposensitivity in alcohol use
Biases in outcome processing, mediated by the mesocortical dopaminergic (DA) system,
may predict individual differences in the frequency and quantity of alcohol use. We tested …
may predict individual differences in the frequency and quantity of alcohol use. We tested …
Behavioral and neural manifestations of reward memory in carriers of low-expressing versus high-expressing genetic variants of the dopamine D2 receptor
Dopamine is critically important in the neural manifestation of motivated behavior, and
alterations in the human dopaminergic system have been implicated in the etiology of …
alterations in the human dopaminergic system have been implicated in the etiology of …
Are alcohol trajectories a useful way of identifying at-risk youth? A multiwave longitudinal-epidemiologic study
Objective Trajectory approaches are a popular way of identifying subgroups of children and
adolescents at high risk for developing alcohol use problems. However, mounting evidence …
adolescents at high risk for developing alcohol use problems. However, mounting evidence …
DAT1 methylation changes in alcohol-dependent individuals vs. controls
A Jasiewicz, B Rubiś, J Samochowiec, I Małecka… - Journal of Psychiatric …, 2015 - Elsevier
Introduction The dopaminergic system plays a crucial role in the development of alcohol
dependence. Regulation of the extracellular dopamine concentration is driven by dopamine …
dependence. Regulation of the extracellular dopamine concentration is driven by dopamine …
An animal model of differential genetic risk for methamphetamine intake
TJ Phillips, S Shabani - Frontiers in neuroscience, 2015 - frontiersin.org
The question of whether genetic factors contribute to risk for methamphetamine (MA) use
and dependence has not been intensively investigated. Compared to human populations …
and dependence has not been intensively investigated. Compared to human populations …