[HTML][HTML] Current approaches of nanomedicines in the market and various stage of clinical translation

X Shan, X Gong, J Li, J Wen, Y Li, Z Zhang - Acta Pharmaceutica Sinica B, 2022 - Elsevier
Compared with traditional drug therapy, nanomedicines exhibit intriguing biological features
to increase therapeutic efficiency, reduce toxicity and achieve targeting delivery. This review …

[HTML][HTML] New-age vaccine adjuvants, their development, and future perspective

SK Verma, P Mahajan, NK Singh, A Gupta… - Frontiers in …, 2023 - frontiersin.org
In the present scenario, immunization is of utmost importance as it keeps us safe and
protects us from infectious agents. Despite the great success in the field of vaccinology …

A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates

MG Joyce, HAD King, I Elakhal-Naouar… - Science translational …, 2021 - science.org
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
stresses the continued need for next-generation vaccines that confer broad protection …

[HTML][HTML] Malaria vaccines: recent advances and new horizons

SJ Draper, BK Sack, CR King, CM Nielsen, JC Rayner… - Cell host & …, 2018 - cell.com
The development of highly effective and durable vaccines against the human malaria
parasites Plasmodium falciparum and P. vivax remains a key priority. Decades of endeavor …

[HTML][HTML] The multirole of liposomes in therapy and prevention of infectious diseases

R Nisini, N Poerio, S Mariotti, F De Santis… - Frontiers in …, 2018 - frontiersin.org
Liposomes are closed bilayer structures spontaneously formed by hydrated phospholipids
that are widely used as efficient delivery systems for drugs or antigens, due to their capability …

Current approaches to HIV vaccine development: a narrative review

J Kim, S Vasan, JH Kim, JA Ake - Journal of the International …, 2021 - Wiley Online Library
Introduction The development of an effective vaccine to protect against HIV is a longstanding
global health need complicated by challenges inherent to HIV biology and to the execution …

[HTML][HTML] Natural and synthetic saponins as vaccine adjuvants

P Wang - Vaccines, 2021 - mdpi.com
Saponin adjuvants have been extensively studied for their use in veterinary and human
vaccines. Among them, QS-21 stands out owing to its unique profile of immunostimulating …

[HTML][HTML] Liposomes as adjuvants and vaccine delivery systems

DS Tretiakova, EL Vodovozova - … Series A: Membrane and Cell Biology, 2022 - Springer
The review considers liposomes as systems of substantial interest as adjuvant carriers in
vaccinology due to their versatility and maximal biocompatibility. Research and …

[HTML][HTML] The continued advance of vaccine adjuvants–'we can work it out'

DT O'Hagan, RN Lodaya, G Lofano - Seminars in immunology, 2020 - Elsevier
In the last decade there have been some significant advances in vaccine adjuvants,
particularly in relation to their inclusion in licensed products. This was proceeded by several …

[HTML][HTML] Messenger RNA expressing PfCSP induces functional, protective immune responses against malaria in mice

KL Mallory, JA Taylor, X Zou, IN Waghela… - npj Vaccines, 2021 - nature.com
Human malaria affects the vast majority of the world's population with the Plasmodium
falciparum species causing the highest rates of morbidity and mortality. With no licensed …