Children differ from adults in many aspects of pharmacotherapy, including capabilities for
drug administration, medicine-related toxicity, and taste preferences. It is essential that …

The passage of the Best Pharmaceuticals for Children Act and the Pediatric Research Equity
Act has collectively resulted in an improvement in rational prescribing for children, including …

The term off-label drug use (OLDU) is used extensively in the medical literature, continuing
medical education exercises, and the media. Yet, we propose that many health care …

A growing number of youth suffer from obesity and in particular severe obesity for which
intensive lifestyle intervention does not adequately reduce excess adiposity. A treatment gap …

Purpose The aim of this review is to assess the extent of the use of off-label and/or
unlicenced drugs among hospitalised children. Methods A systematic search was made in …

Systematic research and practice guidelines addressing preschool psychopharmacological
treatment in very young children are limited, despite evidence of increasing clinical use of …

Off-label prescribing is an integral part of contemporary medicine. Many patients benefit
when they receive drugs or devices under circumstances not specified on the label …

BACKGROUND AND OBJECTIVES: Hospitalized infants, children, and adolescents are
typically exposed to numerous distinct medications during inpatient admissions, increasing …

Background: Worldwide, in the absence of standard pediatric prescribing information,
clinicians often use medicines in children in a dosage form or for an indication that has not …

Objectives: In paediatric pharmacotherapy, many drugs are prescribed to be given in ways
and for conditions not approved in the marketing authorization (MA). Thus, off‐label …