Production of inflammatory cytokines plays important roles in the response against tissue
injury and in host defense. Alterations in the production of inflammatory cytokines may cause …

Dysregulation of peroxisome proliferator-activated receptor gamma (PPARγ) activity leads to
significant alterations in cardiovascular and metabolic regulation. This is most keenly …

Bavachinin (BVC) is a natural small molecule from the Chinese herb Fructus Psoraleae. It
exhibits numerous pharmacological effects, including anti-cancer, anti-inflammation, anti …

Aims Salt-sensitive (SS) hypertension is accompanied by impaired vasodilation in the
systemic and renal circulation. However, the causal relationship between vascular …

The ligand activated nuclear receptor peroxisome proliferator-activated receptor γ (PPARγ)
in the endothelium regulates vascular function and blood pressure (BP). We previously …

We previously showed that impaired vasodilation in systemic and renal vessels contributes
to salt-sensitive hypertension in a mouse model of impaired PPARγ (peroxisome proliferator …

Background Multifunctional calcium/calmodulin‐dependent kinase II (Ca MKII) is activated
by angiotensin II (Ang II) in cultured vascular smooth muscle cells (VSMCs), but its function …

Molecular mechanisms regulating vascular tone by peroxisome... : Current Opinion in
Nephrology and Hypertension Molecular mechanisms regulating vascular tone by …

Loss of peroxisome proliferator–activated receptor-γ (PPARγ) function causes hypertension,
whereas its activation lowers blood pressure. Evidence suggests that these effects may be …

Background: The cholinergic anti-inflammatory pathway (CAIP) has been proposed as a key
mechanism by which the brain, through the vagus nerve (VN), modulates the immune …