Integrin activation

DA Calderwood - Journal of cell science, 2004 - journals.biologists.com
The ability of cells to regulate dynamically their adhesion to one another and to the
extracellular matrix (ECM) that surrounds them is essential in multicellular organisms. The …

[PDF][PDF] The platelet membrane glycoprotein IIb-IIIa complex

DR Phillips, IF Charo, LV Parise, LA Fitzgerald - 1988 - researchgate.net
By David R. Phillips, Israel F. Charo, Leslie V. Parise, and Laurence A. Fitzgerald A NEW
FAMILY of cell-surface receptors has been identified that mediates a wide variety of cell-cell …

T-cell receptor cross-linking transiently stimulates adhesiveness through LFA-1

ML Dustin, TA Springer - Nature, 1989 - nature.com
Effective interaction between T cells and their targets requires that recognition of specific
antigen be coordinated with increased cell-cell adhesion. We show that antigen-receptor …

Two-color nanoscopy of three-dimensional volumes by 4Pi detection of stochastically switched fluorophores

D Aquino, A Schönle, C Geisler, CV Middendorff… - Nature …, 2011 - nature.com
We demonstrate three-dimensional (3D) super-resolution imaging of stochastically switched
fluorophores distributed across whole cells. By evaluating the higher moments of the …

Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.

Z Werb, PM Tremble, O Behrendtsen… - The Journal of cell …, 1989 - rupress.org
We have investigated the effects of ligation of the fibronectin receptor (FnR) on gene
expression in rabbit synovial fibroblasts. Monoclonal antibodies to the FnR that block initial …

[PDF][PDF] Role of lymphocyte adhesion receptors in transient interactions and cell locomotion

ML Dustin, TA Springer - Annual review of immunology, 1991 - researchgate.net
ROLE OF LYMPHOCYTE ADHESION RECEPTORS IN TRANSIENT INTERACTIONS AND CELL
LOCOMOTION Page 1 Annu. Rev. Immunol. 1991.9.’27~66 Copyright © 1991 by Annual …

Increased Platelet Aggregability Associated With Platelet GPIIIa PlA2 Polymorphism The Framingham Offspring Study

DL Feng, K Lindpaintner, MG Larson… - … , and vascular biology, 1999 - Am Heart Assoc
The platelet glycoprotein IIb/IIIa (GP IIb/IIIa) plays a pivotal role in platelet aggregation.
Recent data suggest that the Pl A2 polymorphism of GPIIIa may be associated with an …

The primacy of affinity over clustering in regulation of adhesiveness of the integrin αLβ2

M Kim, CV Carman, W Yang, A Salas… - The Journal of cell …, 2004 - rupress.org
Dynamic regulation of integrin adhesiveness is required for immune cell–cell interactions
and leukocyte migration. Here, we investigate the relationship between cell adhesion and …

Platelets in hemostasis and thrombosis: role of integrins and their ligands

H Ni, J Freedman - Transfusion and Apheresis Science, 2003 - Elsevier
Platelet adhesion and aggregation at the site of vascular injury are two key events in
hemostasis and thrombosis. The contribution of several platelet receptors and their ligands …

Platelet-derived nitric oxide signaling and regulation

E Gkaliagkousi, J Ritter, A Ferro - Circulation research, 2007 - Am Heart Assoc
Nitric oxide (NO) exerts important vasodilatory, antiplatelet, antioxidant, antiadhesive, and
antiproliferative effects. Although endothelium derived NO has been shown to be of prime …