Passive immunotherapy against SARS-CoV-2: from plasma-based therapy to single potent antibodies in the race to stay ahead of the variants
The COVID-19 pandemic is now approaching 2 years old, with more than 440 million people
infected and nearly six million dead worldwide, making it the most significant pandemic …
infected and nearly six million dead worldwide, making it the most significant pandemic …
Pathogenesis and treatment of cytokine storm in COVID-19
COVID-19 is a viral infection caused by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) that killed a large number of patients around the world. A hyperinflammatory …
(SARS-CoV-2) that killed a large number of patients around the world. A hyperinflammatory …
Efficacy of IVIG (intravenous immunoglobulin) for corona virus disease 2019 (COVID-19): A meta-analysis
H Xiang, X Cheng, Y Li, W Luo, Q Zhang… - International …, 2021 - Elsevier
Background The benefit of IVIG (Intravenous Immunoglobulin) therapy for COVID-19
remains controversial. We performed a meta-analysis to investigate the efficacy of IVIG …
remains controversial. We performed a meta-analysis to investigate the efficacy of IVIG …
A phase II safety and efficacy study on prognosis of moderate pneumonia in coronavirus disease 2019 patients with regular intravenous immunoglobulin therapy
RS Raman, V Bhagwan Barge… - The Journal of …, 2021 - academic.oup.com
Background Currently, there is no specific drug for the treatment of coronavirus disease
2019 (COVID-19). Therapeutic benefits of intravenous immunoglobulin (IVIG) have been …
2019 (COVID-19). Therapeutic benefits of intravenous immunoglobulin (IVIG) have been …
Relaxed peripheral tolerance drives broad de novo autoreactivity in severe COVID-19
An emerging feature of COVID-19 is the identification of autoreactivity in patients with severe
disease that may contribute to disease pathology, however the origin and resolution of these …
disease that may contribute to disease pathology, however the origin and resolution of these …
Potential drug development and therapeutic approaches for clinical intervention in COVID-19
While the vaccination is now available to many countries and will slowly dissipate to others,
effective therapeutics for COVID-19 is still illusive. The SARS-CoV-2 pandemic has posed …
effective therapeutics for COVID-19 is still illusive. The SARS-CoV-2 pandemic has posed …
COVID-19-specific transcriptomic signature detectable in blood across multiple cohorts
T Välikangas, S Junttila, KT Rytkönen… - Frontiers in …, 2022 - frontiersin.org
The coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is spreading across the world despite vast global …
syndrome coronavirus 2 (SARS-CoV-2) is spreading across the world despite vast global …
Targeting macrophage dysregulation for viral infections: Novel targets for immunomodulators
MD Reece, RR Taylor, C Song… - Frontiers in …, 2021 - frontiersin.org
A major barrier to human immunodeficiency virus (HIV-1) cure is the latent viral reservoir,
which persists despite antiretroviral therapy (ART), including across the non-dividing …
which persists despite antiretroviral therapy (ART), including across the non-dividing …
A Molecular Biomarker-Based Triage Approach for Targeted Treatment of Post-COVID-19 Syndrome Patients with Persistent Neurological or Neuropsychiatric …
PC Guest, A Neyazi, RC Braun-Dullaeus… - Application of Omic …, 2023 - Springer
Abstract Approximately 30% of COVID-19 cases may experience chronic symptoms, known
as post-COVID-19 syndrome (PCS). Common PCS symptoms can include fatigue, cognitive …
as post-COVID-19 syndrome (PCS). Common PCS symptoms can include fatigue, cognitive …
[HTML][HTML] Insight into the emerging role of SARS-CoV-2 nonstructural and accessory proteins in modulation of multiple mechanisms of host innate defense
Abstract Coronavirus disease-19 (COVID-19) is an extremely infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has become a major …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has become a major …