During aging the immune system (IS) undergoes remarkable changes that collectively are
known as immunosenescence. It is a multifactorial and dynamic phenomenon that affects …

Acute inflammation is a critical host defense response during viral infection. When
dysregulated, inflammation drives immunopathology and tissue damage. Excessive …

Background/objectives Obesity decreases the secretion of SARS-CoV-2-specific IgG
antibodies in the blood of COVID-19 patients. How obesity impacts the quality of the …

Background SARS-CoV-2 seroconversion rate after COVID-19 may be influenced by
disease-modifying therapies (DMTs) in patients with multiple sclerosis (MS) or neuromyelitis …

Background A major challenge of the SARS-CoV-2 pandemic is to better define" protective
thresholds" to guide the global response. We aimed to characterize the longitudinal …

Obesity increases the risk of type 2 diabetes mellitus, cardiovascular disease, fatty liver
disease, and cancer. It is also linked with more severe complications from infections …

Obesity is strongly and independently associated with an increased risk of severe illness
and death from coronavirus disease 2019 (COVID-19). The pathophysiological changes that …

The comprehension of a long-term humoral immune response against SARS-CoV-2 can
shed light on the treatment and vaccination strategies of COVID-19 disease, improving the …

In the 2 years since the COVID‐19 pandemic was officially declared, science has made
considerable strides in understanding the disease's pathophysiology, pharmacological …

The COVID-19 pandemic demonstrates that obesity alone, independent of comorbidities, is
a significant risk factor for severe outcomes from infection. This susceptibility mirrors a …