[HTML][HTML] Novel SARS-CoV-2 variants: the pandemics within the pandemic
Background Many new variants of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) have been termed variants of concern/interest (VOC/I) because of the greater …
(SARS-CoV-2) have been termed variants of concern/interest (VOC/I) because of the greater …
Emergence and rapid spread of a new severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) lineage with multiple spike mutations in South Africa
Continued uncontrolled transmission of the severe acute respiratory syndrome-related
coronavirus 2 (SARS-CoV-2) in many parts of the world is creating the conditions for …
coronavirus 2 (SARS-CoV-2) in many parts of the world is creating the conditions for …
The next phase of SARS-CoV-2 surveillance: real-time molecular epidemiology
The current coronavirus disease 2019 (COVID-19) pandemic is the first to apply whole-
genome sequencing near to real time, with over 2 million severe acute respiratory syndrome …
genome sequencing near to real time, with over 2 million severe acute respiratory syndrome …
LY-CoV1404 (bebtelovimab) potently neutralizes SARS-CoV-2 variants
K Westendorf, S Žentelis, L Wang, D Foster… - Cell reports, 2022 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-neutralizing monoclonal
antibodies (mAbs) can reduce the risk of hospitalization from coronavirus disease 2019 …
antibodies (mAbs) can reduce the risk of hospitalization from coronavirus disease 2019 …
Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016
Monoclonal antibodies and antibody cocktails are a promising therapeutic and prophylaxis
for coronavirus disease 2019 (COVID-19). However, ongoing evolution of severe acute …
for coronavirus disease 2019 (COVID-19). However, ongoing evolution of severe acute …
Minimally instrumented SHERLOCK (miSHERLOCK) for CRISPR-based point-of-care diagnosis of SARS-CoV-2 and emerging variants
The COVID-19 pandemic highlights the need for diagnostics that can be rapidly adapted
and deployed in a variety of settings. Several SARS-CoV-2 variants have shown worrisome …
and deployed in a variety of settings. Several SARS-CoV-2 variants have shown worrisome …
Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies
Monoclonal antibodies targeting a variety of epitopes have been isolated from individuals
previously infected with SARS-CoV-2, but the relative contributions of these different …
previously infected with SARS-CoV-2, but the relative contributions of these different …
[HTML][HTML] Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations
Antibodies elicited by infection accumulate somatic mutations in germinal centers that can
increase affinity for cognate antigens. We analyzed 6 independent groups of clonally related …
increase affinity for cognate antigens. We analyzed 6 independent groups of clonally related …
The variant gambit: COVID-19's next move
More than a year after its emergence, COVID-19, the disease caused by SARS-CoV-2,
continues to plague the world and dominate our daily lives. Even with the development of …
continues to plague the world and dominate our daily lives. Even with the development of …
[HTML][HTML] SARS-CoV-2 501Y. V2 variants lack higher infectivity but do have immune escape
Q Li, J Nie, J Wu, L Zhang, R Ding, H Wang, Y Zhang… - Cell, 2021 - cell.com
The 501Y. V2 variants of SARS-CoV-2 containing multiple mutations in spike are now
dominant in South Africa and are rapidly spreading to other countries. Here, experiments …
dominant in South Africa and are rapidly spreading to other countries. Here, experiments …