[HTML][HTML] Tracking cryptic SARS-CoV-2 lineages detected in NYC wastewater
DS Smyth, M Trujillo, DA Gregory, K Cheung… - Nature …, 2022 - nature.com
Tracking SARS-CoV-2 genetic diversity is strongly indicated because diversifying selection
may lead to the emergence of novel variants resistant to naturally acquired or vaccine …
may lead to the emergence of novel variants resistant to naturally acquired or vaccine …
[HTML][HTML] Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies
The evolution of SARS-CoV-2 could impair recognition of the virus by human antibody-
mediated immunity. To facilitate prospective surveillance for such evolution, we map how …
mediated immunity. To facilitate prospective surveillance for such evolution, we map how …
[HTML][HTML] Transmission, infectivity, and antibody neutralization of an emerging SARS-CoV-2 variant in California carrying a L452R spike protein mutation
We identified a novel SARS-CoV-2 variant by viral whole-genome sequencing of 2,172
nasal/nasopharyngeal swab samples from 44 counties in California. Named B. 1.427/B …
nasal/nasopharyngeal swab samples from 44 counties in California. Named B. 1.427/B …
The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism
Vaccination-based exposure to spike protein derived from early SARS-CoV-2 sequences is
the key public health strategy against COVID-19. Successive waves of SARS-CoV-2 …
the key public health strategy against COVID-19. Successive waves of SARS-CoV-2 …
[HTML][HTML] Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift
The recently emerged SARS-CoV-2 Omicron variant encodes 37 amino acid substitutions in
the spike protein, 15 of which are in the receptor-binding domain (RBD), thereby raising …
the spike protein, 15 of which are in the receptor-binding domain (RBD), thereby raising …
[HTML][HTML] SARS-COV-2 variants: differences and potential of immune evasion
SM Hirabara, TDA Serdan, R Gorjao… - Frontiers in cellular …, 2022 - frontiersin.org
The structural spike (S) glycoprotein of severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) plays an essential role in infection and is an important target for neutralizing …
(SARS-CoV-2) plays an essential role in infection and is an important target for neutralizing …
[HTML][HTML] N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2
Summary The SARS-CoV-2 spike (S) glycoprotein contains an immunodominant receptor-
binding domain (RBD) targeted by most neutralizing antibodies (Abs) in COVID-19 patient …
binding domain (RBD) targeted by most neutralizing antibodies (Abs) in COVID-19 patient …
SARS-CoV-2 mutations and their viral variants
Mutations in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occur
spontaneously during replication. Thousands of mutations have accumulated and continue …
spontaneously during replication. Thousands of mutations have accumulated and continue …
[HTML][HTML] Immune evasion of SARS-CoV-2 emerging variants: what have we learnt so far?
I Lazarevic, V Pravica, D Miljanovic, M Cupic - Viruses, 2021 - mdpi.com
Despite the slow evolutionary rate of SARS-CoV-2 relative to other RNA viruses, its massive
and rapid transmission during the COVID-19 pandemic has enabled it to acquire significant …
and rapid transmission during the COVID-19 pandemic has enabled it to acquire significant …
[HTML][HTML] The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies
Monoclonal antibodies against SARS-CoV-2 are a clinically validated therapeutic option
against COVID-19. Because rapidly emerging virus mutants are becoming the next major …
against COVID-19. Because rapidly emerging virus mutants are becoming the next major …