Genomic sequence and chromosomal location of human interleukin-11 gene (IL11)

D McKinley, Q Wu, T Yang-Feng, YC Yang - Genomics, 1992 - Elsevier
The genomic sequence of human interleukin-11 (IL11) has been isolated based on its
sequence homology with a cDNA clone encoding primate IL11. The human IL11 genomic …

IL-1 and transforming growth factor-beta regulation of fibroblast-derived IL-11.

JA Elias, T Zheng, NL Whiting, TK Trow… - … (Baltimore, Md.: 1950 …, 1994 - journals.aai.org
Abstract IL-11 and IL-6 are fibroblast-derived cytokines with overlapping biologic properties.
To determine whether IL-11 and IL-6 are similarly regulated, we characterized the effects of …

Interleukin-11 stimulates multiple phases of erythropoiesis in vitro

VF Quesniaux, SC Clark, K Turner, B Fagg - 1992 - ashpublications.org
Abstract Interleukin-11 (IL-11), a pleiotropic cytokine originally isolated from a primate bone
marrow stromal cell line, has been shown to stimulate T-cell-dependent B-cell maturation …

Computational EST database analysis identifies a novel member of the neuropoietic cytokine family

Y Shi, W Wang, PA Yourey, S Gohari… - Biochemical and …, 1999 - Elsevier
A novel member of the neuropoietic cytokine family has been cloned and the protein
expressed and characterized. In an effort to identify novel secreted proteins, an algorithm …

Interleukin-11 reduces T-cell-dependent experimental liver injury in mice

M Bozza, JL Bliss, R Maylor, J Erickson, L Donnelly… - Hepatology, 1999 - journals.lww.com
Abstract Recombinant human interleukin-11 (rhIL-11) is a multifunctional cytokine that can
reduce inflammation through the downregulation of multiple pro-inflammatory mediators …

Recombinant human interleukin-11 stimulates multilineage hematopoietic recovery in mice after a myelosuppressive regimen of sublethal irradiation and carboplatin

JP Leonard, CM Quinto, MK Kozitza, TY Neben… - 1994 - ashpublications.org
Abstract Interleukin-11 (IL-11) is a novel multifunctional hematopoietic cytokine capable of
stimulating cells of the myeloid, lymphoid, erythroid, and megakaryocytic lineages in vitro …

An anti‐inflammatory role for interleukin‐11 in established murine collagen‐induced arthritis

WALMSLEY, FELDMANN - Immunology, 1998 - Wiley Online Library
Interleukin‐11 (IL‐11) is a cytokine belonging to the IL‐6 family which has both pro‐and anti‐
inflammatory potential. Like IL‐6 it can diminish tumour necrosis factor‐α and IL‐1 …

Preclinical biology of interleukin 11: a multifunctional hematopoietic cytokine with potent thrombopoietic activity

SJ Goldman - Stem cells, 1995 - academic.oup.com
Abstract Interleukin 11 (IL-11) is a multifunctional hematopoietic cytokine which was
originally identified as a factor produced by an IL-l-stimulated primate stromal cell line. The …

[HTML][HTML] Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein

S Chevalier, M Fourcin, O Robledo, J Wijdenes… - Journal of Biological …, 1996 - ASBMB
Gp130 transducing protein was shown to be involved in the formation of the high affinity
receptors for interleukin 6 (IL-6), interleukin-11 (IL-11), leukemia inhibitory factor, oncostatin …

[HTML][HTML] Mitogen-activated protein kinases and ribosomal S6 protein kinases are involved in signaling pathways shared by interleukin-11, interleukin-6, leukemia …

T Yin, YC Yang - Journal of Biological Chemistry, 1994 - Elsevier
The mechanisms of signaling pathways shared by interleukin (IL)-11, IL-6, leukemia
inhibitory factor (LIF), and oncostatin M (ONC) remain elusive. We report here that treatment …