Thrombocytopoietic properties of oncostatin M

PM Wallace, JF MacMaster, JR Rillema, J Peng… - 1995 - ashpublications.org
Oncostatin M (OM) is a 28-kD glycoprotein that exhibits a panoply of biologic effects. Based
on histologic observations of increased splenic megakaryocytes in nude mice implanted …

Trophic effects of interleukin-11 in rats with experimental short bowel syndrome

Q Liu, XX Du, DT Schindel, ZX Yang… - Journal of pediatric …, 1996 - Elsevier
Interleukin-11 (IL-11) is a multifunctional cytokine, derived from bone marrow stromal cells,
that stimulates proliferation of stem/progenitor precursor cells in the small intestinal crypts …

IL-11 inhibits Clostridium difficile toxin A enterotoxicity in rat ileum

I Castagliuolo, CP Kelly, BS Qiu… - American Journal …, 1997 - journals.physiology.org
Interleukin-11 (IL-11) is a stromal cell-derived cytokine with several biological activities
against hematopoietic cells. Recent results indicated that IL-11 reduced mucosal damage in …

The biology of interleukin 11

S Neben, K Turner - Stem Cells, 1993 - Wiley Online Library
Abstract Interleukin 11 (IL‐11) is a multifunctional cytokine which may play a role in
regulating the growth and development of cells in both the hematopoietic and lymphoid …

Synergism between interleukin-11 and bone morphogenetic protein-2 in the healing of segmental bone defects in a rabbit model

K Suga, M Saitoh, S Kokubo, K Nozaki… - Journal of interferon & …, 2004 - liebertpub.com
Recombinant human interleukin-11 (rHuIL-11) and recombinant human bone
morphogenetic protein-2 (rHuBMP-2) have been shown to act synergistically in the induction …

Involvement of gp130/interleukin‐6 receptor transducing component in interleukin‐11 receptor

M Fourcin, S Chevalier, JJ Lebrun… - European journal of …, 1994 - Wiley Online Library
The recently cloned interleukin (IL)‐11 displays many biological properties in common with
those reported for IL‐6. In order to analyze the nature and the functionality of the IL‐11 …

Effects of the active metabolite of leflunomide, A77 1726, on cytokine release and the MAPK signalling pathway in human rheumatoid arthritis synoviocytes

P Vergne-Salle, DY Léger, P Bertin, R Trèves… - Cytokine, 2005 - Elsevier
Inflammatory cytokines or soluble factors are essential in the pathogenesis of rheumatoid
arthritis (RA). Leflunomide is an effective disease modifying antirheumatic drug (DMARD) in …

Interleukin 11: an overview

YC Yang - Stem Cells, 1993 - Wiley Online Library
Interleukin (IL)‐ll is a bone marrow fibroblast derived cytokine with a wide spectrum of in
vitro biological activities in the hematopoietic, lymphopoietic, hepatic, adipose, neuronal and …

The cloning and biological characterization of recombinant human interleukin 11

SR Paul, P Schendel - The International Journal of Cell Cloning, 1992 - Wiley Online Library
Abstract Interleukin 11 (IL‐11) is a pleiotropic hematopoietic growth factor with stimulatory
effects on multiple hematopoietic progenitor cells. An immortalized primate bone marrow …

Cysteinyl leukotriene upregulates IL-11 expression in allergic airway disease of mice

KS Lee, SR Kim, HS Park, SJ Park, KH Min… - Journal of allergy and …, 2007 - Elsevier
BACKGROUND: Chronic airway inflammation and airway remodeling are important features
of bronchial asthma. IL-11 is one of the important mediators involved in the process of …