In our previous studies aiming at the design of appropriate to accelerate the recovery of the
system after irradiation we found that recombinant murine (rmu) It-3 treatment induc3es …

gp130 transducing receptor is involved in the formation of high affinity receptors for the
cytokines of the interleukin-6 (IL-6) family. Recruitment of gp130 by IL-6 associated to its …

Interleukin-11 (IL-11) is a bone marrow microenvironment-derived growth factor with
pleiotropic effects on a variety of hematopoietic cells. To more accurately assess the effects …

We previously demonstrated that recombinant human interleukin-11 (rHuIL-11) induced
osteoblast differentiation of C3H10T1/2 progenitor cells and also acted synergistically with …

B lymphocytes, the cellular source of antibody, are critical components of the immune
response. They develop from multipotential stem cells, progressively acquiring the traits that …

In one aspect the present invention provides a novel mammalian cytokine, called IL-11,
which is substantially free from other mammalian proteins. This protein may be produced by …

Abstract Interleukin-11 (IL-11) is a pleiotropic cytokine with effects on many different targets.
Within the hematopoietic system, the effects of IL-11 are largely manifest only through …

The issue of whether interleukin-11 (IL-11) contributes to bone loss during states of estrogen
deficiency has not been previously determined. We therefore randomized ovariectomized …

The role of interleukin‐11 (IL‐11) was evaluated in the IgG immune complex model of acute
lung injury in rats. IL‐11 mRNA and protein were both up‐regulated during the course of this …

Megakaryocytopoiesis is the cellular system which sustains platelet production. Platelets are
the blood cell which play a major role in hemostasis by their capacity for adhesion to the …