Gene therapy: Comprehensive overview and therapeutic applications

N Sayed, P Allawadhi, A Khurana, V Singh, U Navik… - Life sciences, 2022 - Elsevier
Gene therapy is the product of man's quest to eliminate diseases. Gene therapy has three
facets namely, gene silencing using siRNA, shRNA and miRNA, gene replacement where …

Superoxide dismutase nanozymes: an emerging star for anti-oxidation

H Zhao, R Zhang, X Yan, K Fan - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Superoxide dismutases (SODs) are a group of metalloenzymes that catalyze the dismutation
of superoxide radicals (O2˙−) into hydrogen peroxide (H2O2) and oxygen (O2). As the first …

Role of nanotechnology behind the success of mRNA vaccines for COVID-19

A Khurana, P Allawadhi, I Khurana, S Allwadhi… - Nano Today, 2021 - Elsevier
The emergency use authorization (EUA) by the US-FDA for two mRNA-based vaccines
BNT162b2 (Pfizer-BioNTech) and mRNA-1273 (Moderna) has brought hope of addressing …

An overview on nanoparticle-based strategies to fight viral infections with a focus on COVID-19

S Yasamineh, HG Kalajahi, P Yasamineh… - Journal of …, 2022 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to COVID-19 and has
become a pandemic worldwide with mortality of millions. Nanotechnology can be used to …

Nanoceria, the versatile nanoparticles: Promising biomedical applications

MA Saifi, S Seal, C Godugu - Journal of Controlled Release, 2021 - Elsevier
Nanotechnology has been a boon for the biomedical field due to the freedom it provides for
tailoring of pharmacokinetic properties of different drug molecules. Nanomedicine is the …

CeO2 Nanoparticle-Containing Polymers for Biomedical Applications: A Review

AB Shcherbakov, VV Reukov, AV Yakimansky… - Polymers, 2021 - mdpi.com
The development of advanced composite biomaterials combining the versatility and
biodegradability of polymers and the unique characteristics of metal oxide nanoparticles …

A systematic review on COVID-19 vaccine strategies, their effectiveness, and issues

SS Khandker, B Godman, MI Jawad, BA Meghla… - Vaccines, 2021 - mdpi.com
COVID-19 vaccines are indispensable, with the number of cases and mortality still rising,
and currently no medicines are routinely available for reducing morbidity and mortality, apart …

Apoptosis and pharmacological therapies for targeting thereof for cancer therapeutics

V Singh, A Khurana, U Navik, P Allawadhi, KK Bharani… - Sci, 2022 - mdpi.com
Apoptosis is an evolutionarily conserved sequential process of cell death to maintain a
homeostatic balance between cell formation and cell death. It is a vital process for normal …

Recent advances in graphene quantum dot-based optical and electrochemical (bio) analytical sensors

A Kalkal, S Kadian, R Pradhan, G Manik… - Materials …, 2021 - pubs.rsc.org
Since the day of their origin, the graphene quantum dots (GQDs) have been considered a
predominant material for biosensing applications in view of their unique and exciting …

Biomedical applications of polysaccharide nanoparticles for chronic inflammatory disorders: Focus on rheumatoid arthritis, diabetes and organ fibrosis

P Allawadhi, V Singh, K Govindaraj, I Khurana… - Carbohydrate …, 2022 - Elsevier
Polysaccharides are biopolymers distinguished by their complex secondary structures
executing various roles in microorganisms, plants, and animals. They are made up of long …