Plasmonic Nanograin Metasurface with Disorder‐Enhanced Biosensing for SARS‐CoV‐2 Variant and Antibodies

F Li, C Guan, K Chen, Y Jiang, Y Xie… - Advanced Functional …, 2024 - Wiley Online Library
Recently, the concept of introducing disorder into ordered metasurfaces or periodic
metastructures has shown great potential in improving their performance for light extraction …

Preclinical efficacy, safety, and immunogenicity of PHH-1V, a second-generation COVID-19 vaccine candidate based on a novel recombinant RBD fusion heterodimer …

A Barreiro, A Prenafeta, G Bech-Sabat, M Roca… - BioRxiv, 2021 - biorxiv.org
Since the genetic sequence of SARS-CoV-2 became available in January 2020, new
vaccines have been developed at an unprecedented speed. The current vaccines have …

A bacterially expressed SARS-CoV-2 receptor binding domain fused with cross-reacting material 197 a-domain elicits high level of neutralizing antibodies in mice

L Liu, T Chen, L Zhou, J Sun, Y Li, M Nie… - Frontiers in …, 2022 - frontiersin.org
The Coronavirus disease 2019 (COVID-19) pandemic presents an unprecedented public
health crisis worldwide. Although several vaccines are available, the global supply of …

Effective prophylaxis of COVID-19 in rhesus macaques using a combination of two parenterally-administered SARS-CoV-2 neutralizing antibodies

BJ Beddingfield, NJ Maness, AC Fears… - Frontiers in Cellular …, 2021 - frontiersin.org
SARS-CoV-2 is a respiratory borne pathogenic beta coronavirus that is the source of a
worldwide pandemic and the cause of multiple pathologies in man. The rhesus macaque …

Measles Virus-Based Vaccine Expressing Membrane-Anchored Spike of SARS-CoV-2 Inducing Efficacious Systemic and Mucosal Humoral Immunity in Hamsters

ZH Yang, YL Song, J Pei, SZ Li, RL Liu, Y Xiong, J Wu… - Viruses, 2024 - mdpi.com
As SARS-CoV-2 continues to evolve and COVID-19 cases rapidly increase among children
and adults, there is an urgent need for a safe and effective vaccine that can elicit systemic …

Molecular basis of broad neutralization against SARS-CoV-2 variants including Omicron by a human antibody

B Ju, Q Zheng, H Guo, Q Fan, T Li, S Song, H Sun… - bioRxiv, 2022 - biorxiv.org
Omicron, a newly emerging SARS-CoV-2 variant, carried a large number of mutations in the
spike protein leading to an unprecedented evasion from many neutralizing antibodies …

[HTML][HTML] An easy pipeline for one-step purification of SARS-CoV-2 nucleocapsid protein from insect cell suspension culture

BR de Camargo, LA da Silva, AS de Oliveira… - Journal of virological …, 2022 - Elsevier
The COVID-19 pandemic has demanded a range of biotechnological products for detection
of SARS-CoV-2 variants and evaluation of human seroconversion after infection or …

In-solution buffer-free digestion for the analysis of SARS-CoV-2 RBD proteins allows a full sequence coverage and detection of post-translational modifications in a …

LA Espinosa, Y Ramos, I Andújar, EO Torres… - BioRxiv, 2021 - biorxiv.org
Subunit vaccines based on the receptor-binding domain (RBD) of the spike protein of SARS-
CoV-2, are among the most promising strategies to fight the COVID-19 pandemic. The …

Potent neutralization antibodies induced by a recombinant trimeric spike protein vaccine candidate containing PIKA adjuvant for COVID-19

J Tong, C Zhu, H Lai, C Feng, D Zhou - Vaccines, 2021 - mdpi.com
The structures of immunogens that elicit the most potent neutralization antibodies to prevent
COVID-19 infection are still under investigation. In this study, we tested the efficacy of a …

[PDF][PDF] COVID-19 molecular level laboratory diagnoses.

M Pohanka - Bratislava Medical Journal/Bratislavské Lekárske …, 2021 - researchgate.net
ABSTRACT AIMS: Aims: The Coronavirus Disease 2019 (COVID-19) caused not only global
pandemic, but it also pointed at unprepared health care systems and countermeasures were …