The production of recombinant proteins using insect cells has been widely used for over 30
years, which contributing to life science research and biotechnology. Insect cells exhibiting …

In December 2019, an outbreak of a respiratory disease called the coronavirus disease
2019 (COVID-19) caused by a new coronavirus known as severe acute respiratory …

Background The baculovirus expression vector system has been developed for expressing
a wide range of proteins, including enzymes, glycoproteins, recombinant viruses, and …

The increase in confirmed COVID-19 cases and SARS-CoV-2 variants calls for the
development of safe and broad cross-protective vaccines. The RBD of the spike protein was …

This study focuses on the development and initial assessment of an indirect IgG enzyme-
linked immunosorbent assay (ELISA) specifically designed to detect of anti-SARS-CoV-2 …

Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus-2 (SARSCoV-2) is still surging across the globe and has …

Concerns over vaccine efficacy after the emergence of the SARS-CoV-2 Delta variant
prompted revisiting the vaccine design concepts. Monoclonal antibodies (mAbs) have been …

In vitro cell culture practices are valuable techniques to understand the mechanisms behind
vital in vivo biological processes. In vitro cells have helped us to attain a deeper …

Cleavage of the furin site in SARS-CoV-2 spike (S) protein accounts for increased
transmissibility of COVID-19 by promoting the entry of virus into host cells through specific …

We describe an analytical method for the identification, mapping and relative quantitation of
glycopeptides from SARS-CoV-2 Spike protein. The method may be executed using a LC …