Bioorthogonal chemistry

SL Scinto, DA Bilodeau, R Hincapie, W Lee… - Nature Reviews …, 2021 - nature.com
Bioorthogonal chemistry represents a class of high-yielding chemical reactions that proceed
rapidly and selectively in biological environments without side reactions towards …

Light-triggered click chemistry

GS Kumar, Q Lin - Chemical reviews, 2020 - ACS Publications
The merging of click chemistry with discrete photochemical processes has led to the creation
of a new class of click reactions, collectively known as photoclick chemistry. These light …

Developing bioorthogonal probes to span a spectrum of reactivities

SS Nguyen, JA Prescher - Nature Reviews Chemistry, 2020 - nature.com
Bioorthogonal chemistries enable researchers to interrogate biomolecules in living systems.
These reactions are highly selective and biocompatible, and can be performed in many …

Alkane desaturation by concerted double hydrogen atom transfer to benzyne

D Niu, PH Willoughby, BP Woods, B Baire, TR Hoye - Nature, 2013 - nature.com
The removal of two vicinal hydrogen atoms from an alkane to produce an alkene is a
challenge for synthetic chemists,. In nature, desaturases and acetylenases are adept at …

Glycans in pathogenic bacteria–potential for targeted covalent therapeutics and imaging agents

VN Tra, DH Dube - Chemical Communications, 2014 - pubs.rsc.org
A substantial obstacle to the existing treatment of bacterial diseases is the lack of specific
probes that can be used to diagnose and treat pathogenic bacteria in a selective manner …

Organoboron compounds as versatile reagents in the transition metal-catalyzed C–S, C–Se and C–Te bond formation

AM Barcellos, M Sacramento, GP da Costa… - Coordination Chemistry …, 2021 - Elsevier
Organochalcogen compounds present synthetic and biological applications of extreme
relevance. The coupling reaction between boronic acids, borate anions or boronic esters …

Accelerated neural differentiation of mouse embryonic stem cells on aligned GYIGSR-functionalized nanofibers

EA Silantyeva, W Nasir, J Carpenter, O Manahan… - Acta biomaterialia, 2018 - Elsevier
Substrates for embryonic stem cell culture are typified by poorly defined xenogenic, whole
proteins or cellular components that are difficult and expensive to generate, characterize …

Photochemical formation of dibenzosilacyclohept-4-yne for Cu-free click chemistry with azides and 1, 2, 4, 5-Tetrazines

M Martínek, L Filipová, J Galeta, L Ludvíková… - Organic letters, 2016 - ACS Publications
Photochemical generation of dibenzosilacyclohept-4-yne 3 from the corresponding
cyclopropenone 1 and its copper-free click reactions are reported. Steady-state irradiation …

Contemporary catalyst-free photochemistry in synthetic macromolecular science

BT Tuten, S Wiedbrauk, C Barner-Kowollik - Progress in Polymer Science, 2020 - Elsevier
The spatiotemporal control that light affords the polymer chemists is one of the most powerful
tools at their disposal. Photochemistry has been an integral part to the development of …

[HTML][HTML] Photochemical syntheses, transformations, and bioorthogonal chemistry of trans-cycloheptene and sila trans-cycloheptene Ag (I) complexes

Y Fang, H Zhang, Z Huang, SL Scinto, JC Yang… - Chemical …, 2018 - pubs.rsc.org
A photochemical synthesis of AgNO3 complexes of trans-cycloheptene (TCH) and trans-1-
sila-4-cycloheptene (Si-TCH) derivatives is described. A low temperature flow photoreactor …