Implantation is the first step in human reproduction. Successful implantation depends on the
crosstalk between embryo and endometrium. Recurrent implantation failure (RIF) is a …

The CRISPR/Cas9 system is a rapid, simple, and often extremely efficient gene editing
method. This method has been used in a variety of organisms and cell types over the past …

Visual morphology assessment is routinely used for evaluating of embryo quality and
selecting human blastocysts for transfer after in vitro fertilization (IVF). However, the …

Objective To study how the attributes of mosaicism identified during preimplantation genetic
testing for aneuploidy relate to clinical outcomes, in order to formulate a ranking system of …

Genome editing is a powerful new tool for making precise alterations to an organism's
genetic material. Recent scientific advances have made genome editing more efficient …

Healthy Babies after Intrauterine Transfer of Mosaic Aneuploid Blastocysts | New England Journal
of Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Preimplantation genetic testing for aneuploidy (PGT-A) with trophectoderm (TE) biopsy is
widely applied in in vitro fertilization (IVF) to identify aneuploid embryos. However, potential …

Objective To investigate the parameters of mosaicism and the biological mechanisms
leading to healthy pregnancies from mosaic embryo transfers. Design Prospective study …

BACKGROUND Trophectoderm (TE) biopsy and next generation sequencing (NGS) are
currently the preferred techniques for preimplantation genetic testing for aneuploidies (PGT …

Post-zygotic variation refers to genetic changes that arise in the soma of an individual and
that are not usually inherited by the next generation. Although there is a paucity of research …