The health risks associated with transferring embryos classified as mosaic by
preimplantation genetic testing for aneuploidies (PGT-A) are currently unknown. Such …

STUDY QUESTION Are chromosome abnormalities detected at Day 3 post-fertilization
predominantly retained in structures of the blastocyst other than the inner cell mass (ICM) …

The discovery of CRISPR: Cas9 and its application as a powerful gene-editing tool has
transformed the world of basic and applied science, especially the molecular biology dome …

The underlying cause of cancer is genetic disruption, so gene editing technologies,
particularly CRISPR/Cas systems can be used to go against cancer. The field of gene …

Purpose To evaluate the incidence of mosaicism in de novo neurofibromatosis 2 (NF2).
Methods Patients fulfilling NF2 criteria, but with no known affected family member from a …

The first mitosis of the mammalian embryo must partition the parental genomes contained in
two pronuclei. In rodent zygotes, sperm centrosomes are degraded, and instead, acentriolar …

Defining the actual incidence and prevalence of mosaicism in human blastocysts still
remains a difficult task. The small amount of evidence generated by animal and human …

Designed to minimize chances of transferring genetically abnormal embryos,
preimplantation genetic diagnosis (PGD) involves in vitro fertilization (IVF), embryo biopsy …

Objective To investigate the blastocoelic fluid (BF) for the presence of DNA that could be
amplified and analyzed; the extent to which its chromosomal status corresponds to that …

Purpose Mosaicism is a prevalent characteristic of human preimplantation embryos. This
retrospective cohort study aimed to investigate pregnancy outcomes after transfer of mosaic …