Therapeutic potential of PPARγ natural agonists in liver diseases

L Wu, C Guo, J Wu - Journal of cellular and molecular …, 2020 - Wiley Online Library
Peroxisome proliferator‐activated receptor gamma (PPARγ) is a vital subtype of the PPAR
family. The biological functions are complex and diverse. PPARγ plays a significant role in …

Peroxisome proliferator-activated receptor gamma and its natural agonists in the treatment of kidney diseases

V Sharma, V Patial - Frontiers in Pharmacology, 2022 - frontiersin.org
Kidney disease is one of the leading non-communicable diseases related to tremendous
health and economic burden globally. Diabetes, hypertension, obesity and cardiovascular …

Monascuspiloin from Monascus-Fermented Red Mold Rice Alleviates Alcoholic Liver Injury and Modulates Intestinal Microbiota

L Wu, K Zhou, Z Yang, J Li, G Chen, Q Wu, X Lv, W Hu… - Foods, 2022 - mdpi.com
Monascus-fermented red mold rice (RMR) has excellent physiological efficacy on lipid
metabolism and liver function. This study investigated the ameliorative effects of …

Impact of red yeast rice on metabolic diseases: a review of possible mechanisms of action

J Hu, J Wang, Q Gan, Q Ran, G Lou… - Journal of Agricultural …, 2020 - ACS Publications
Metabolic diseases constitute a major public health burden and are linked with high
morbidity and mortality. They comprise atherosclerosis dyslipidemia, diabetes, hypertension …

Monascin and ankaflavin—Biosynthesis from Monascus purpureus, production methods, pharmacological properties: A review

SN Adin, I Gupta, BP Panda… - … and Applied Biochemistry, 2023 - Wiley Online Library
Monascus purpureus copiously yields beneficial secondary metabolites, including
Monascus pigments, which are broadly used as food additives, as a nitrite substitute in meat …

Alleviation of metabolic syndrome by monascin and ankaflavin: the perspective of Monascus functional foods

CH Lin, TH Lin, TM Pan - Food & function, 2017 - pubs.rsc.org
The metabolites of Monascus with multiple benefits are popular subjects for the
development of functional foods. The yellow pigments, monascin and ankaflavin, which are …

Black mulberry extract inhibits hepatic adipogenesis through AMPK/mTOR signaling pathway in T2DM mice

Y Yao, Y Chen, H Chen, X Pan, X Li, W Liu… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Black mulberry (Morus nigra L.) is an ancient dual-
use plant resource for medicine and food. It is widely used in Uyghur folklore for …

Morin, the PPARγ agonist, inhibits Th17 differentiation by limiting fatty acid synthesis in collagen-induced arthritis

Y Miao, X Wu, X Xue, X Ma, L Yang, X Zeng… - Cell Biology and …, 2023 - Springer
T helper (Th) 17 cells highly contribute to the immunopathology of rheumatoid arthritis.
Morin, a natural flavonoid, owns well anti-arthritic action but unclear effect on Th17 …

Natural products on nonalcoholic fatty liver disease

JY Xu, L Zhang, ZP Li, G Ji - Current Drug Targets, 2015 - ingentaconnect.com
Non-alcoholic fatty liver disease (NAFLD) is a chronic disorder of lipid and carbohydrate
metabolism and is often associated with endoplasmic reticulum stress, energy homeostasis …

A novel PPARgamma agonist monascin's potential application in diabetes prevention

WH Hsu, TM Pan - Food & function, 2014 - pubs.rsc.org
Edible fungi of the Monascus species have been used as traditional Chinese medicine in
eastern Asia for several centuries. Monascus-fermented products possess a number of …