Background Life-long health inequalities exert enduring impacts and are governed by social
determinants crucial for achieving healthy aging. A fundamental aspect of healthy aging …

Aging is the slowest process in a living organism. During this process, mortality rate
increases exponentially due to the accumulation of damage at the cellular level. Cellular …

Brain Development Network, Canadian Institute for Advanced Research and SocioMed
Research 87 Nucleus, Universidad Mayor, Santiago, Chile. DB is an inventor of …

Brain aging is a complex process influenced by various lifestyle, environmental, and genetic
factors, as well as by age-related and often co-existing pathologies. MRI and, more recently …

James German's work to establish the natural history and cancer risk associated with Bloom
syndrome (BS) has had a strong influence on the generation of scientists and clinicians …

Background Chronic obstructive pulmonary disease (COPD) has impacted approximately
390 million people worldwide and the morbidity is increasing every year. However, due to …

Nicotinamide adenine dinucleotide (NAD) can be used as an initiating nucleotide in RNA
transcription to produce NAD-capped RNA (NAD-RNA). RNA modification by NAD that links …

Amyotrophic Lateral Sclerosis (ALS) is a group of sporadic and genetic neurodegenerative
disorders that result in losses of upper and lower motor neurons. Treatment of ALS is limited …

The improvement of human living conditions has led to an increase in average life
expectancy, creating a new social and medical problem—aging, which diminishes the …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19), which has killed~ 7 million persons worldwide. Chronic kidney …